6e13: Difference between revisions
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==Pseudomonas putida PqqB with a non-physiological zinc at the active site binds the substrate mimic, 5-cysteinyl-3,4-dihydroxyphenylalanine (5-Cys-DOPA), non-specifically but supports the proposed function of the enzyme in pyrroloquinoline quinone biosynthesis.== | |||
<StructureSection load='6e13' size='340' side='right'caption='[[6e13]], [[Resolution|resolution]] 2.35Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6e13]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_putida_KT2440 Pseudomonas putida KT2440]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E13 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6E13 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.349Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HKS:3-{[(2S)-2-amino-2-carboxyethyl]sulfanyl}-5-hydroxy-L-tyrosine'>HKS</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
[[Category: Evans | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6e13 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6e13 OCA], [https://pdbe.org/6e13 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6e13 RCSB], [https://www.ebi.ac.uk/pdbsum/6e13 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6e13 ProSAT]</span></td></tr> | ||
[[Category: Wilmot | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/PQQB_PSEPK PQQB_PSEPK] May be involved in the transport of PQQ or its precursor to the periplasm (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Pseudomonas putida KT2440]] | |||
[[Category: Evans III RL]] | |||
[[Category: Wilmot CM]] | |||
Latest revision as of 14:38, 13 March 2024
Pseudomonas putida PqqB with a non-physiological zinc at the active site binds the substrate mimic, 5-cysteinyl-3,4-dihydroxyphenylalanine (5-Cys-DOPA), non-specifically but supports the proposed function of the enzyme in pyrroloquinoline quinone biosynthesis.
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