6eb7: Difference between revisions
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New page: '''Unreleased structure''' The entry 6eb7 is ON HOLD Authors: Riboldi-Tunnicliffe, A., Issacs, N.W. Description: YycF homologue (SP1227) Receiver Domain Activated by BeF3 [[Category: U... |
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==YycF homologue (SP1227) Receiver Domain Activated by BeF3== | |||
<StructureSection load='6eb7' size='340' side='right'caption='[[6eb7]], [[Resolution|resolution]] 1.58Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6eb7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_TIGR4 Streptococcus pneumoniae TIGR4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EB7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6EB7 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.58Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | ||
[[Category: Issacs | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6eb7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6eb7 OCA], [https://pdbe.org/6eb7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6eb7 RCSB], [https://www.ebi.ac.uk/pdbsum/6eb7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6eb7 ProSAT]</span></td></tr> | ||
[[Category: Riboldi-Tunnicliffe | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/WALR_STRPN WALR_STRPN] Member of the two-component regulatory system WalK/WalR that regulates genes involved in cell wall metabolism (By similarity). Binds to the promoter region of the transcription factor fabT gene in the fabTH-acp operon in vitro (PubMed:27610104). Inhibits transcription of fabT, probably acting in an unphosphorylated form, thereby playing a role in the regulation of fatty acid biosynthesis (PubMed:15774879, PubMed:27610104). Essential for normal growth in vitro (By similarity). Required for maintaining normal cellular morphology, acting, at least in part, by regulating peptidoglycan hydrolase pcsB (By similarity). Involved in maintaining expression of WalRK regulon genes in exponentially growing cells (By similarity).[UniProtKB:A0A0H2ZN37][UniProtKB:P37478][UniProtKB:Q8DPL7]<ref>PMID:15774879</ref> <ref>PMID:27610104</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Streptococcus pneumoniae TIGR4]] | |||
[[Category: Issacs NW]] | |||
[[Category: Riboldi-Tunnicliffe A]] | |||
Latest revision as of 13:14, 13 August 2026
YycF homologue (SP1227) Receiver Domain Activated by BeF3
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