6ed3: Difference between revisions

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~~'''Unreleased structure'''~~

~~The entry~~ 6ed3 is ~~ON HOLD~~

==Mtb ClpB in complex with AMPPNP==

== Structural highlights ==

<table><tr><td colspan='2'>[[6ed3]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ED3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ED3 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 6.3Å</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ed3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ed3 OCA], [https://pdbe.org/6ed3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ed3 RCSB], [https://www.ebi.ac.uk/pdbsum/6ed3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ed3 ProSAT]</span></td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/CLPB_MYCTU CLPB_MYCTU] Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).

~~Authors~~:

==See Also==

*[[Heat Shock Protein structures|Heat Shock Protein structures]]

~~Description~~:

*[[3D structures of ClpB|3D structures of ClpB]]

[[Category: ~~Unreleased Structures~~]]

__TOC__

</SX>

[[Category: Large Structures]]

[[Category: Mycobacterium tuberculosis]]

[[Category: Li HL]]

[[Category: Yu HJ]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6ed3 is ON HOLD
+==Mtb ClpB in complex with AMPPNP==
+<SX load='6ed3' size='340' side='right' viewer='molstar' caption='[[6ed3]], [[Resolution|resolution]] 6.30&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6ed3]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ED3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ED3 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 6.3&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ed3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ed3 OCA], [https://pdbe.org/6ed3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ed3 RCSB], [https://www.ebi.ac.uk/pdbsum/6ed3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ed3 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/CLPB_MYCTU CLPB_MYCTU] Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
-Authors:
+==See Also==
+*[[Heat Shock Protein structures|Heat Shock Protein structures]]
-Description:
+*[[3D structures of ClpB|3D structures of ClpB]]
-[[Category: Unreleased Structures]]
+__TOC__
+</SX>
+[[Category: Large Structures]]
+[[Category: Mycobacterium tuberculosis]]
+[[Category: Li HL]]
+[[Category: Yu HJ]]