2n5z: Difference between revisions

<StructureSection load='2n5z' size='340' side='right'caption='[[2n5z]]' scene=''>

<table><tr><td colspan='2'>[[2n5z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N5Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2N5Z FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2n5z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n5z OCA], [https://pdbe.org/2n5z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2n5z RCSB], [https://www.ebi.ac.uk/pdbsum/2n5z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2n5z ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/RPFC_MYCTU RPFC_MYCTU] Factor that stimulates resuscitation of dormant cells. Has peptidoglycan (PG) hydrolytic activity. Active in the pM concentration range. Has little to no effect on actively-growing cells. PG fragments could either directly activate the resuscitation pathway of dormant bacteria or serve as a substrate for endogenous Rpf, resulting in low molecular weight products with resuscitation activity.<ref>PMID:12410821</ref>  Stimulates growth of stationary phase M.bovis (a slow-growing Mycobacterium), reduces the lag phase of diluted fast-growers M.smegmatis and Micrococcus luteus. Sequential gene disruption indicates RpfB and RpfE are higher than RpfD and RpfC in functional hierarchy.<ref>PMID:12410821</ref>  

[[Category: Large Structures]]

[[Category: Mycobacterium tuberculosis H37Rv]]

[[Category: Isernia C]]

[[Category: Maione V]]

[[Category: Russo L]]