2n1n: Difference between revisions

<StructureSection load='2n1n' size='340' side='right'caption='[[2n1n]]' scene=''>

<table><tr><td colspan='2'>[[2n1n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Grammostola_rosea Grammostola rosea]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N1N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2N1N FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2n1n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n1n OCA], [https://pdbe.org/2n1n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2n1n RCSB], [https://www.ebi.ac.uk/pdbsum/2n1n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2n1n ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/VSTX1_GRARO VSTX1_GRARO] Inhibits sodium channels Nav1.7/SCN9A and potassium channels Kv11.1/KCNH2. Also binds the voltage-sensor domain of the potassium channel KvAP (from the archaeon Aeropyrum pernix) with very slow apparent binding kinetics and affects channel gating. Reaches its target by dynamically partitioning into anionic or zwitterionic headgroup lipid membranes. May bind to the open state of KvAP.<ref>PMID:15241419</ref> <ref>PMID:15287735</ref> <ref>PMID:17002285</ref> <ref>PMID:19955179</ref>  

[[Category: Grammostola rosea]]

[[Category: Large Structures]]

[[Category: King GF]]

[[Category: Lau HY]]

[[Category: Mobli M]]