6eec: Difference between revisions
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==Mycobacterium tuberculosis RNAP promoter unwinding intermediate complex with RbpA/CarD and AP3 promoter captured by Corallopyronin== | |||
<SX load='6eec' size='340' side='right' viewer='molstar' caption='[[6eec]], [[Resolution|resolution]] 3.55Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6eec]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EEC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6EEC FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.55Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C0L:methyl+~{N}-[(~{E},5~{R})-5-[4,6-bis(oxidanylidene)-5-[(2~{E},4~{E},8~{R},9~{E},12~{E})-2,5,9-trimethyl-1,8-bis(oxidanyl)tetradeca-2,4,9,12-tetraenylidene]pyran-2-yl]hex-1-enyl]carbamate'>C0L</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6eec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6eec OCA], [https://pdbe.org/6eec PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6eec RCSB], [https://www.ebi.ac.uk/pdbsum/6eec PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6eec ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/RPOA_MYCTU RPOA_MYCTU] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_00059]<ref>PMID:22570422</ref> | |||
==See Also== | |||
*[[Sigma factor 3D structures|Sigma factor 3D structures]] | |||
== References == | |||
[[Category: | <references/> | ||
[[Category: Boyaci Selcuk | __TOC__ | ||
[[Category: | </SX> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Darst | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Boyaci Selcuk H]] | |||
[[Category: Campbell EA]] | |||
[[Category: Chen J]] | |||
[[Category: Darst SA]] | |||
Latest revision as of 08:44, 4 June 2025
Mycobacterium tuberculosis RNAP promoter unwinding intermediate complex with RbpA/CarD and AP3 promoter captured by Corallopyronin
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