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==High resolution crystal structure of FtsY-NG domain of E. coli==
==High resolution crystal structure of FtsY-NG domain of E. coli==
<StructureSection load='6cqp' size='340' side='right' caption='[[6cqp]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
<StructureSection load='6cqp' size='340' side='right'caption='[[6cqp]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6cqp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CQP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CQP FirstGlance]. <br>
<table><tr><td colspan='2'>[[6cqp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CQP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CQP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.446&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cqp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cqp OCA], [http://pdbe.org/6cqp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cqp RCSB], [http://www.ebi.ac.uk/pdbsum/6cqp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cqp ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6cqp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cqp OCA], [https://pdbe.org/6cqp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6cqp RCSB], [https://www.ebi.ac.uk/pdbsum/6cqp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6cqp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FTSY_ECOLI FTSY_ECOLI]] Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.<ref>PMID:8194520</ref> <ref>PMID:9305630</ref> <ref>PMID:11735405</ref> <ref>PMID:11741850</ref> <ref>PMID:15148364</ref> <ref>PMID:17682051</ref>
[https://www.uniprot.org/uniprot/FTSY_ECOLI FTSY_ECOLI] Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.<ref>PMID:8194520</ref> <ref>PMID:9305630</ref> <ref>PMID:11735405</ref> <ref>PMID:11741850</ref> <ref>PMID:15148364</ref> <ref>PMID:17682051</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6cqp" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6cqp" style="background-color:#fffaf0;"></div>
==See Also==
*[[Signal recognition particle receptor|Signal recognition particle receptor]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ataide, S F]]
[[Category: Escherichia coli K-12]]
[[Category: Faoro, C]]
[[Category: Large Structures]]
[[Category: Cotranslational delivery srp]]
[[Category: Ataide SF]]
[[Category: Protein transport]]
[[Category: Faoro C]]
Retrieved from "https://proteopedia.org/6cqp"