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[[Image:2pcr.jpg|left|200px]]


{{Structure
==Crystal structure of Myo-inositol-1(or 4)-monophosphatase (aq_1983) from Aquifex Aeolicus VF5==
|PDB= 2pcr |SIZE=350|CAPTION= <scene name='initialview01'>2pcr</scene>, resolution 2.60&Aring;
<StructureSection load='2pcr' size='340' side='right'caption='[[2pcr]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>
<table><tr><td colspan='2'>[[2pcr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PCR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PCR FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Inositol-phosphate_phosphatase Inositol-phosphate phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.25 3.1.3.25] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pcr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pcr OCA], [https://pdbe.org/2pcr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pcr RCSB], [https://www.ebi.ac.uk/pdbsum/2pcr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pcr ProSAT], [https://www.topsan.org/Proteins/RSGI/2pcr TOPSAN]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pcr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pcr OCA], [http://www.ebi.ac.uk/pdbsum/2pcr PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2pcr RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/BSUHB_AQUAE BSUHB_AQUAE] Phosphatase with broad specificity; it can dephosphorylate fructose 1,6-bisphosphate, and both D and L isomers of inositol-1-phosphate (I-1-P).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pc/2pcr_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pcr ConSurf].
<div style="clear:both"></div>


'''Crystal structure of Myo-inositol-1(or 4)-monophosphatase (aq_1983) from Aquifex Aeolicus VF5'''
==See Also==
 
*[[Inositol monophosphatase 3D structures|Inositol monophosphatase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2PCR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PCR OCA].
[[Category: Aquifex aeolicus VF5]]
[[Category: Aquifex aeolicus]]
[[Category: Large Structures]]
[[Category: Inositol-phosphate phosphatase]]
[[Category: Agari Y]]
[[Category: Single protein]]
[[Category: Antonyuk SV]]
[[Category: Agari, Y.]]
[[Category: Bessho Y]]
[[Category: Antonyuk, S V.]]
[[Category: Ebihara A]]
[[Category: Bessho, Y.]]
[[Category: Ellis MJ]]
[[Category: Ebihara, A.]]
[[Category: Gayathri D]]
[[Category: Ellis, M J.]]
[[Category: Hasnain SS]]
[[Category: Gayathri, D.]]
[[Category: Jeyakanthan J]]
[[Category: Hasnain, S S.]]
[[Category: Kuramitsu S]]
[[Category: Jeyakanthan, J.]]
[[Category: Shinkai A]]
[[Category: Kuramitsu, S.]]
[[Category: Shiro Y]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Strange RW]]
[[Category: Shinkai, A.]]
[[Category: Velmurugan D]]
[[Category: Shiro, Y.]]
[[Category: Yokoyama S]]
[[Category: Strange, R W.]]
[[Category: Velmurugan, D.]]
[[Category: Yokoyama, S.]]
[[Category: bipolar disorder]]
[[Category: hydrolase]]
[[Category: myo-inositol monophosphatase(impa)]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:34:18 2008''
Retrieved from "https://proteopedia.org/2pcr"