6h23: Difference between revisions
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==Crystal structure of the hClpP Y118A mutant with an activating small molecule== | ==Crystal structure of the hClpP Y118A mutant with an activating small molecule== | ||
<StructureSection load='6h23' size='340' side='right' caption='[[6h23]], [[Resolution|resolution]] 3.09Å' scene=''> | <StructureSection load='6h23' size='340' side='right'caption='[[6h23]], [[Resolution|resolution]] 3.09Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6h23]] is a 14 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H23 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6H23 FirstGlance]. <br> | <table><tr><td colspan='2'>[[6h23]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H23 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6H23 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FJT:~{N}-(1,3-benzodioxol-5-ylmethyl)-5-[(2-chloranyl-4-fluoranyl-phenyl)methyl]-1,3,4-oxadiazole-2-carboxamide'>FJT</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FJT:~{N}-(1,3-benzodioxol-5-ylmethyl)-5-[(2-chloranyl-4-fluoranyl-phenyl)methyl]-1,3,4-oxadiazole-2-carboxamide'>FJT</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CLPP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endopeptidase_Clp Endopeptidase Clp], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.92 3.4.21.92] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endopeptidase_Clp Endopeptidase Clp], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.92 3.4.21.92] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6h23 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h23 OCA], [http://pdbe.org/6h23 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6h23 RCSB], [http://www.ebi.ac.uk/pdbsum/6h23 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6h23 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6h23 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h23 OCA], [http://pdbe.org/6h23 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6h23 RCSB], [http://www.ebi.ac.uk/pdbsum/6h23 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6h23 ProSAT]</span></td></tr> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Endopeptidase Clp]] | [[Category: Endopeptidase Clp]] | ||
[[Category: Human]] | |||
[[Category: Large Structures]] | |||
[[Category: Kick, L M]] | [[Category: Kick, L M]] | ||
[[Category: Schneider, S]] | [[Category: Schneider, S]] | ||
Latest revision as of 08:15, 3 April 2019
Crystal structure of the hClpP Y118A mutant with an activating small molecule
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