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[[Image:2pml.jpg|left|200px]]


{{Structure
==Crystal structure of PfPK7 in complex with an ATP analogue==
|PDB= 2pml |SIZE=350|CAPTION= <scene name='initialview01'>2pml</scene>, resolution 2.60&Aring;
<StructureSection load='2pml' size='340' side='right'caption='[[2pml]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>
<table><tr><td colspan='2'>[[2pml]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PML OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PML FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
|GENE= PFB0605w ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 Plasmodium falciparum])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pml FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pml OCA], [https://pdbe.org/2pml PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pml RCSB], [https://www.ebi.ac.uk/pdbsum/2pml PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pml ProSAT]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pml FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pml OCA], [http://www.ebi.ac.uk/pdbsum/2pml PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2pml RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/O96214_PLAFA O96214_PLAFA]
 
== Evolutionary Conservation ==
'''Crystal structure of PfPK7 in complex with an ATP analogue'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pm/2pml_consurf.spt"</scriptWhenChecked>
2PML is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PML OCA].  
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pml ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Plasmodium falciparum]]
[[Category: Plasmodium falciparum]]
[[Category: Single protein]]
[[Category: Echalier A]]
[[Category: Echalier, A.]]
[[Category: Endicott J]]
[[Category: Endicott, J.]]
[[Category: Merckx A]]
[[Category: Merckx, A.]]
[[Category: Noble M]]
[[Category: Noble, M.]]
[[Category: phosphorylation]]
[[Category: plasmodium falciparum]]
[[Category: ser/thr protein kinase]]
[[Category: transferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:37:59 2008''

Latest revision as of 09:10, 21 February 2024

Crystal structure of PfPK7 in complex with an ATP analogue

2pml, resolution 2.60Å

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