6c56: Difference between revisions
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==Crystal structure of mutant human geranylgeranyl pyrophosphate synthase (Y246D) in its Apo form== | ==Crystal structure of mutant human geranylgeranyl pyrophosphate synthase (Y246D) in its Apo form== | ||
<StructureSection load='6c56' size='340' side='right' caption='[[6c56]], [[Resolution|resolution]] 2.80Å' scene=''> | <StructureSection load='6c56' size='340' side='right'caption='[[6c56]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6c56]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C56 OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[6c56]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C56 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6C56 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=VT0: | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=VT0:[[(2-phenylthieno[2,3-d]pyrimidin-4-yl)amino]-phosphono-methyl]phosphonic+acid'>VT0</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6c56 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c56 OCA], [https://pdbe.org/6c56 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6c56 RCSB], [https://www.ebi.ac.uk/pdbsum/6c56 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6c56 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/GGPPS_HUMAN GGPPS_HUMAN] Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 6c56" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 6c56" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Geranylgeranyl pyrophosphate synthase 3D structures|Geranylgeranyl pyrophosphate synthase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Berghuis AM]] | ||
[[Category: | [[Category: Park J]] | ||
[[Category: | [[Category: Ta V]] | ||
[[Category: | [[Category: Tsantrizos YS]] | ||
Latest revision as of 07:51, 17 October 2024
Crystal structure of mutant human geranylgeranyl pyrophosphate synthase (Y246D) in its Apo form
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