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==Solution structure of the C-terminal acidic domain of TFIIE alpha==
==Solution structure of the C-terminal acidic domain of TFIIE alpha==
<StructureSection load='2rnq' size='340' side='right' caption='[[2rnq]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2rnq' size='340' side='right'caption='[[2rnq]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2rnq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RNQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RNQ FirstGlance]. <br>
<table><tr><td colspan='2'>[[2rnq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RNQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RNQ FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1vd4|1vd4]], [[1d8j|1d8j]], [[1d8k|1d8k]], [[2rnr|2rnr]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rnq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rnq OCA], [http://pdbe.org/2rnq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2rnq RCSB], [http://www.ebi.ac.uk/pdbsum/2rnq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2rnq ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rnq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rnq OCA], [https://pdbe.org/2rnq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rnq RCSB], [https://www.ebi.ac.uk/pdbsum/2rnq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rnq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/T2EA_HUMAN T2EA_HUMAN]] Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.  
[https://www.uniprot.org/uniprot/T2EA_HUMAN T2EA_HUMAN] Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Transcription initiation factor|Transcription initiation factor]]
*[[Transcription initiation factors 3D structures|Transcription initiation factors 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Nishimura, Y]]
[[Category: Large Structures]]
[[Category: Okuda, M]]
[[Category: Nishimura Y]]
[[Category: Acidic domain]]
[[Category: Okuda M]]
[[Category: General transcription factor]]
[[Category: Human tfiie alpha]]
[[Category: Human tfiih p62]]
[[Category: Ph domain]]
[[Category: Transcription]]
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