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==Complement component polyC9==
==Complement component polyC9==
<StructureSection load='6dlw' size='340' side='right' caption='[[6dlw]], [[Resolution|resolution]] 3.90&Aring;' scene=''>
<SX load='6dlw' size='340' side='right' viewer='molstar' caption='[[6dlw]], [[Resolution|resolution]] 3.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6dlw]] is a 22 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DLW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DLW FirstGlance]. <br>
<table><tr><td colspan='2'>[[6dlw]] is a 22 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DLW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6DLW FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.9&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dlw OCA], [http://pdbe.org/6dlw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dlw RCSB], [http://www.ebi.ac.uk/pdbsum/6dlw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dlw ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6dlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dlw OCA], [https://pdbe.org/6dlw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6dlw RCSB], [https://www.ebi.ac.uk/pdbsum/6dlw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6dlw ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/CO9_HUMAN CO9_HUMAN]] Age-related macular degeneration;Immunodeficiency due to a late component of complements deficiency. Disease susceptibility is associated with variations affecting the gene represented in this entry.  Disease susceptibility is associated with variations affecting the gene represented in this entry.  
[https://www.uniprot.org/uniprot/CO9_HUMAN CO9_HUMAN] Age-related macular degeneration;Immunodeficiency due to a late component of complements deficiency. Disease susceptibility is associated with variations affecting the gene represented in this entry.  Disease susceptibility is associated with variations affecting the gene represented in this entry.
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CO9_HUMAN CO9_HUMAN]] Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC.  
[https://www.uniprot.org/uniprot/CO9_HUMAN CO9_HUMAN] Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</SX>
[[Category: Dunstone, M A]]
[[Category: Homo sapiens]]
[[Category: Law, R H.P]]
[[Category: Large Structures]]
[[Category: Spicer, B A]]
[[Category: Dunstone MA]]
[[Category: Complement]]
[[Category: Law RHP]]
[[Category: Em]]
[[Category: Spicer BA]]
[[Category: Immune system]]
[[Category: Membrane]]
[[Category: Pore]]
[[Category: Transmembrane]]
Retrieved from "https://proteopedia.org/6dlw"