4ym9: Difference between revisions
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==Crystal structure of Porcine Pancreatic Elastase (PPE) in complex with the novel inhibitor JM102== | ==Crystal structure of Porcine Pancreatic Elastase (PPE) in complex with the novel inhibitor JM102== | ||
<StructureSection load='4ym9' size='340' side='right' caption='[[4ym9]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='4ym9' size='340' side='right'caption='[[4ym9]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4ym9]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4ym9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YM9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YM9 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4E4:2-ETHYL-2-(HYDROXYMETHYL)-N-(6-METHYLPYRIDIN-3-YL)BUTANAMIDE'>4E4</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4E4:2-ETHYL-2-(HYDROXYMETHYL)-N-(6-METHYLPYRIDIN-3-YL)BUTANAMIDE'>4E4</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ym9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ym9 OCA], [https://pdbe.org/4ym9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ym9 RCSB], [https://www.ebi.ac.uk/pdbsum/4ym9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ym9 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/CELA1_PIG CELA1_PIG] Acts upon elastin. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 19: | Line 19: | ||
</div> | </div> | ||
<div class="pdbe-citations 4ym9" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4ym9" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Elastase 3D structures|Elastase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Sus scrofa]] | [[Category: Sus scrofa]] | ||
[[Category: Archer | [[Category: Archer M]] | ||
[[Category: Brito | [[Category: Brito JA]] | ||
[[Category: Hofbauer | [[Category: Hofbauer S]] | ||
[[Category: Moreira | [[Category: Moreira R]] | ||
[[Category: Mulchande | [[Category: Mulchande J]] | ||
[[Category: Nogly | [[Category: Nogly P]] | ||
[[Category: Pessanha | [[Category: Pessanha M]] | ||
Latest revision as of 10:55, 10 January 2024
Crystal structure of Porcine Pancreatic Elastase (PPE) in complex with the novel inhibitor JM102
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