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==2.7A crystal structure of inorganic pyrophosphatase (Rv3628) from Mycobacterium tuberculosis at pH 7.5==
==2.7A crystal structure of inorganic pyrophosphatase (Rv3628) from Mycobacterium tuberculosis at pH 7.5==
<StructureSection load='2uxs' size='340' side='right' caption='[[2uxs]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='2uxs' size='340' side='right'caption='[[2uxs]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2uxs]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UXS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2UXS FirstGlance]. <br>
<table><tr><td colspan='2'>[[2uxs]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UXS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2UXS FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1sxv|1sxv]], [[1wcf|1wcf]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Inorganic_diphosphatase Inorganic diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.1 3.6.1.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2uxs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uxs OCA], [https://pdbe.org/2uxs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2uxs RCSB], [https://www.ebi.ac.uk/pdbsum/2uxs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2uxs ProSAT], [https://www.topsan.org/Proteins/RSGI/2uxs TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2uxs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uxs OCA], [http://pdbe.org/2uxs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2uxs RCSB], [http://www.ebi.ac.uk/pdbsum/2uxs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2uxs ProSAT], [http://www.topsan.org/Proteins/RSGI/2uxs TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/IPYR_MYCTU IPYR_MYCTU]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Inorganic pyrophosphatase|Inorganic pyrophosphatase]]
*[[Inorganic pyrophosphatase 3D structures|Inorganic pyrophosphatase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Inorganic diphosphatase]]
[[Category: Large Structures]]
[[Category: Myctu]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Cianci, M]]
[[Category: Cianci M]]
[[Category: Cole, R E]]
[[Category: Cole RE]]
[[Category: Hall, J F]]
[[Category: Hall JF]]
[[Category: Hasnain, S S]]
[[Category: Hasnain SS]]
[[Category: Kigawa, T]]
[[Category: Kigawa T]]
[[Category: Matsuda, T]]
[[Category: Matsuda T]]
[[Category: Tabernero, L]]
[[Category: Tabernero L]]
[[Category: Yokoyama, S]]
[[Category: Yokoyama S]]
[[Category: Hydrolase]]
[[Category: Inorganic pyrophosphatase]]
[[Category: Magnesium]]
[[Category: Metal-binding]]
[[Category: Ppase]]
[[Category: Rv3628]]

Latest revision as of 14:57, 13 December 2023

2.7A crystal structure of inorganic pyrophosphatase (Rv3628) from Mycobacterium tuberculosis at pH 7.5

2uxs, resolution 2.70Å

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