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==Crystal structure of the D55E mutant of the HupR receiver domain==
==Crystal structure of the D55E mutant of the HupR receiver domain==
<StructureSection load='2vuh' size='340' side='right' caption='[[2vuh]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='2vuh' size='340' side='right'caption='[[2vuh]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2vuh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"rhodonostoc_capsulatum"_molisch_1907 "rhodonostoc capsulatum" molisch 1907]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VUH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VUH FirstGlance]. <br>
<table><tr><td colspan='2'>[[2vuh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodobacter_capsulatus Rhodobacter capsulatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VUH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VUH FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jk1|2jk1]], [[2vui|2vui]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vuh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vuh OCA], [http://pdbe.org/2vuh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vuh RCSB], [http://www.ebi.ac.uk/pdbsum/2vuh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vuh ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vuh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vuh OCA], [https://pdbe.org/2vuh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vuh RCSB], [https://www.ebi.ac.uk/pdbsum/2vuh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vuh ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/HUPR_RHOCA HUPR_RHOCA]] Probable member of the two-component regulatory system involved in the regulation of the [NiFe] hydrogenase activity. HupR1 is probably phosphorylated by the sensory component and then acts in conjunction with sigma-54 as a transcriptional activator.  
[https://www.uniprot.org/uniprot/HUPR_RHOCA HUPR_RHOCA] Probable member of the two-component regulatory system involved in the regulation of the [NiFe] hydrogenase activity. HupR1 is probably phosphorylated by the sensory component and then acts in conjunction with sigma-54 as a transcriptional activator.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Rhodonostoc capsulatum molisch 1907]]
[[Category: Large Structures]]
[[Category: Davies, K M]]
[[Category: Rhodobacter capsulatus]]
[[Category: Johnson, L N]]
[[Category: Davies KM]]
[[Category: Lowe, E D]]
[[Category: Johnson LN]]
[[Category: Venien-Bryan, C]]
[[Category: Lowe ED]]
[[Category: Activator]]
[[Category: Venien-Bryan C]]
[[Category: Atp-binding]]
[[Category: Beryllium fluoride phosphorylation mimic]]
[[Category: Cytoplasm]]
[[Category: Dna-binding]]
[[Category: Hupr]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Response regulator]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Two-component regulatory system]]
Retrieved from "https://proteopedia.org/2vuh"