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==THE STRUCTURE OF CLOSTRIDIUM PERFRINGENS NANI SIALIDASE AND ITS CATALYTIC INTERMEDIATES==
==THE STRUCTURE OF CLOSTRIDIUM PERFRINGENS NANI SIALIDASE AND ITS CATALYTIC INTERMEDIATES==
<StructureSection load='2vk7' size='340' side='right' caption='[[2vk7]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
<StructureSection load='2vk7' size='340' side='right'caption='[[2vk7]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2vk7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_perfringens"_veillon_and_zuber_1898 "bacillus perfringens" veillon and zuber 1898]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VK7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VK7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2vk7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_perfringens Clostridium perfringens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VK7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VK7 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FSI:5-(ACETYLAMINO)-3,5-DIDEOXY-3-FLUORO-D-ERYTHRO-ALPHA-L-MANNO-NON-2-ULOPYRANOSONIC+ACID'>FSI</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2bf6|2bf6]], [[2vk5|2vk5]], [[2vk6|2vk6]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FSI:5-(ACETYLAMINO)-3,5-DIDEOXY-3-FLUORO-D-ERYTHRO-ALPHA-L-MANNO-NON-2-ULOPYRANOSONIC+ACID'>FSI</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vk7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vk7 OCA], [https://pdbe.org/2vk7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vk7 RCSB], [https://www.ebi.ac.uk/pdbsum/2vk7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vk7 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vk7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vk7 OCA], [http://pdbe.org/2vk7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vk7 RCSB], [http://www.ebi.ac.uk/pdbsum/2vk7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vk7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q59310_CLOPF Q59310_CLOPF]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vk/2vk7_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vk/2vk7_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus perfringens veillon and zuber 1898]]
[[Category: Clostridium perfringens]]
[[Category: Exo-alpha-sialidase]]
[[Category: Large Structures]]
[[Category: Chien, C H]]
[[Category: Chien CH]]
[[Category: Newstead, S L]]
[[Category: Newstead SL]]
[[Category: Potter, J A]]
[[Category: Potter JA]]
[[Category: Taylor, G L]]
[[Category: Taylor GL]]
[[Category: Watts, A G]]
[[Category: Watts AG]]
[[Category: Wilson, J C]]
[[Category: Wilson JC]]
[[Category: Withers, S G]]
[[Category: Withers SG]]
[[Category: Xu, G]]
[[Category: Xu G]]
[[Category: Clostridium perfringen]]
[[Category: Glycosidase]]
[[Category: Hydrolase]]
[[Category: Sialic acid]]
[[Category: Sialidase]]
Retrieved from "https://proteopedia.org/2vk7"