2w6x: Difference between revisions

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==Crystal structure of Sperm Whale Myoglobin mutant YQRF in complex with Xenon==
==Crystal structure of Sperm Whale Myoglobin mutant YQRF in complex with Xenon==
<StructureSection load='2w6x' size='340' side='right' caption='[[2w6x]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
<StructureSection load='2w6x' size='340' side='right'caption='[[2w6x]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2w6x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Phycd Phycd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W6X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W6X FirstGlance]. <br>
<table><tr><td colspan='2'>[[2w6x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W6X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W6X FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=XE:XENON'>XE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.73&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1cik|1cik]], [[103m|103m]], [[1bvc|1bvc]], [[1vxb|1vxb]], [[4mbn|4mbn]], [[112m|112m]], [[2evp|2evp]], [[1mtk|1mtk]], [[2mge|2mge]], [[1yoh|1yoh]], [[2mgc|2mgc]], [[1f65|1f65]], [[1jdo|1jdo]], [[1lue|1lue]], [[2g0v|2g0v]], [[1tes|1tes]], [[2blj|2blj]], [[1dxc|1dxc]], [[2spl|2spl]], [[2d6c|2d6c]], [[1mlh|1mlh]], [[2w6w|2w6w]], [[1mlm|1mlm]], [[1mlj|1mlj]], [[1mbn|1mbn]], [[2bwh|2bwh]], [[2mgi|2mgi]], [[2g0s|2g0s]], [[1myz|1myz]], [[1n9f|1n9f]], [[1jpb|1jpb]], [[1mls|1mls]], [[1mbd|1mbd]], [[1mti|1mti]], [[106m|106m]], [[1mlo|1mlo]], [[1do3|1do3]], [[1cpw|1cpw]], [[101m|101m]], [[2g0x|2g0x]], [[1vxd|1vxd]], [[1l2k|1l2k]], [[2bli|2bli]], [[1jp9|1jp9]], [[1mlg|1mlg]], [[2mgg|2mgg]], [[1ch9|1ch9]], [[2mbw|2mbw]], [[1vxf|1vxf]], [[111m|111m]], [[2mgj|2mgj]], [[1u7s|1u7s]], [[2blh|2blh]], [[105m|105m]], [[1mbi|1mbi]], [[2w6y|2w6y]], [[1vxh|1vxh]], [[1cp5|1cp5]], [[1mln|1mln]], [[1h1x|1h1x]], [[1f6h|1f6h]], [[1do1|1do1]], [[1spe|1spe]], [[1n9h|1n9h]], [[1myf|1myf]], [[1mll|1mll]], [[1a6g|1a6g]], [[1mbo|1mbo]], [[1ch5|1ch5]], [[102m|102m]], [[1yoi|1yoi]], [[1ltw|1ltw]], [[2spm|2spm]], [[2g0z|2g0z]], [[1hjt|1hjt]], [[1bvd|1bvd]], [[1wvp|1wvp]], [[2myb|2myb]], [[1do4|1do4]], [[1moa|1moa]], [[1ebc|1ebc]], [[1ch1|1ch1]], [[1mym|1mym]], [[1mlk|1mlk]], [[1mlq|1mlq]], [[1mgn|1mgn]], [[1mlf|1mlf]], [[1ch3|1ch3]], [[2spn|2spn]], [[1ch7|1ch7]], [[5mbn|5mbn]], [[1cq2|1cq2]], [[1fcs|1fcs]], [[1moc|1moc]], [[1do7|1do7]], [[2mgh|2mgh]], [[2mb5|2mb5]], [[1mbc|1mbc]], [[2g0r|2g0r]], [[1yog|1yog]], [[1cio|1cio]], [[1jp6|1jp6]], [[1u7r|1u7r]], [[1ofj|1ofj]], [[2g10|2g10]], [[1cp0|1cp0]], [[1ajh|1ajh]], [[109m|109m]], [[2g14|2g14]], [[1duk|1duk]], [[1vxa|1vxa]], [[2bw9|2bw9]], [[1n9i|1n9i]], [[2mye|2mye]], [[1mz0|1mz0]], [[1dti|1dti]], [[1dxd|1dxd]], [[1bzr|1bzr]], [[1mcy|1mcy]], [[1abs|1abs]], [[1f63|1f63]], [[2mgf|2mgf]], [[110m|110m]], [[1swm|1swm]], [[1vxg|1vxg]], [[2g12|2g12]], [[1a6n|1a6n]], [[1n9x|1n9x]], [[1ofk|1ofk]], [[1dtm|1dtm]], [[2myc|2myc]], [[1ufp|1ufp]], [[2spo|2spo]], [[2mgb|2mgb]], [[2mgm|2mgm]], [[1jw8|1jw8]], [[1o16|1o16]], [[1vxc|1vxc]], [[1a6k|1a6k]], [[2mga|2mga]], [[1mlr|1mlr]], [[1irc|1irc]], [[2mgl|2mgl]], [[1ajg|1ajg]], [[1vxe|1vxe]], [[1mtj|1mtj]], [[1mlu|1mlu]], [[1obm|1obm]], [[2mya|2mya]], [[1co9|1co9]], [[1a6m|1a6m]], [[1co8|1co8]], [[2cmm|2cmm]], [[107m|107m]], [[1naz|1naz]], [[108m|108m]], [[2myd|2myd]], [[2jho|2jho]], [[1ch2|1ch2]], [[104m|104m]], [[2g11|2g11]], [[1duo|1duo]], [[1jp8|1jp8]], [[2mgd|2mgd]], [[1mod|1mod]], [[1j3f|1j3f]], [[1j52|1j52]], [[1iop|1iop]], [[1bz6|1bz6]], [[1mob|1mob]], [[2mgk|2mgk]], [[1bzp|1bzp]], [[1ufj|1ufj]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=XE:XENON'>XE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w6x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w6x OCA], [http://pdbe.org/2w6x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w6x RCSB], [http://www.ebi.ac.uk/pdbsum/2w6x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2w6x ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w6x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w6x OCA], [https://pdbe.org/2w6x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w6x RCSB], [https://www.ebi.ac.uk/pdbsum/2w6x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w6x ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MYG_PHYMC MYG_PHYMC]] Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.  
[https://www.uniprot.org/uniprot/MYG_PHYMC MYG_PHYMC] Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w6/2w6x_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w6/2w6x_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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==See Also==
==See Also==
*[[Hemoglobin 3D structures|Hemoglobin 3D structures]]
*[[Hemoglobin 3D structures|Hemoglobin 3D structures]]
*[[Myoglobin|Myoglobin]]
*[[Myoglobin 3D structures|Myoglobin 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Phycd]]
[[Category: Large Structures]]
[[Category: Brunori, M]]
[[Category: Physeter catodon]]
[[Category: Draghi, F]]
[[Category: Brunori M]]
[[Category: Johnson, K A]]
[[Category: Draghi F]]
[[Category: Miele, A E]]
[[Category: Johnson KA]]
[[Category: Renzi, F]]
[[Category: Miele AE]]
[[Category: Savino, C]]
[[Category: Renzi F]]
[[Category: Sciara, G]]
[[Category: Savino C]]
[[Category: Vallone, B]]
[[Category: Sciara G]]
[[Category: Distal site point mutation]]
[[Category: Vallone B]]
[[Category: Heme]]
[[Category: Hydrophobic cavity]]
[[Category: Iron]]
[[Category: Metal-binding]]
[[Category: Muscle protein]]
[[Category: Oxygen storage]]
[[Category: Oxygen transport]]
[[Category: Transport]]
[[Category: Xenon docking site]]

Latest revision as of 17:34, 8 September 2026

Crystal structure of Sperm Whale Myoglobin mutant YQRF in complex with Xenon

2w6x, resolution 1.73Å

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