2wry: Difference between revisions

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==Crystal structure of chicken cytokine interleukin 1 beta==
==Crystal structure of chicken cytokine interleukin 1 beta==
<StructureSection load='2wry' size='340' side='right' caption='[[2wry]], [[Resolution|resolution]] 1.58&Aring;' scene=''>
<StructureSection load='2wry' size='340' side='right'caption='[[2wry]], [[Resolution|resolution]] 1.58&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2wry]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WRY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WRY FirstGlance]. <br>
<table><tr><td colspan='2'>[[2wry]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WRY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WRY FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wry FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wry OCA], [http://pdbe.org/2wry PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wry RCSB], [http://www.ebi.ac.uk/pdbsum/2wry PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wry ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.58&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wry FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wry OCA], [https://pdbe.org/2wry PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wry RCSB], [https://www.ebi.ac.uk/pdbsum/2wry PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wry ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/O73909_CHICK O73909_CHICK]] Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity).[RuleBase:RU003753]  
[https://www.uniprot.org/uniprot/O73909_CHICK O73909_CHICK] Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity).[RuleBase:RU003753]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Interleukin|Interleukin]]
*[[Interleukin 3D structures|Interleukin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Chick]]
[[Category: Gallus gallus]]
[[Category: Cheng, C S]]
[[Category: Large Structures]]
[[Category: Lee, L H]]
[[Category: Cheng CS]]
[[Category: Lu, W S]]
[[Category: Lee LH]]
[[Category: Lyu, P C]]
[[Category: Lu WS]]
[[Category: Wang, W C]]
[[Category: Lyu PC]]
[[Category: Yin, H S]]
[[Category: Wang WC]]
[[Category: Immune system]]
[[Category: Yin HS]]
[[Category: Inflammatory response]]
[[Category: Mitogen]]
[[Category: Pyrogen]]
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