6hrl: Difference between revisions
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==Crystal structure of the Kelch domain of human KLHL17== | |||
<StructureSection load='6hrl' size='340' side='right'caption='[[6hrl]], [[Resolution|resolution]] 2.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6hrl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HRL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6HRL FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6hrl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hrl OCA], [https://pdbe.org/6hrl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6hrl RCSB], [https://www.ebi.ac.uk/pdbsum/6hrl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6hrl ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/KLH17_HUMAN KLH17_HUMAN] Substrate-recognition component of some cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex. The BCR(KLHL17) mediates the ubiquitination and subsequenct degradation of GLUR6. May play a role in the actin-based neuronal function (By similarity). | |||
==See Also== | |||
*[[Kelch-like protein 3D structures|Kelch-like protein 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Arrowsmith F]] | ||
[[Category: | [[Category: Bountra C]] | ||
[[Category: | [[Category: Bullock AN]] | ||
[[Category: Edwards | [[Category: Burgess-Brown N]] | ||
[[Category: | [[Category: Chen Z]] | ||
[[Category: | [[Category: Edwards CH]] | ||
[[Category: | [[Category: Newman JA]] | ||
[[Category: | [[Category: Shrestha L]] | ||
[[Category: | [[Category: Sorrell FJ]] | ||
[[Category: Williams E]] | |||
[[Category: Von Delft F]] | |||
Latest revision as of 11:37, 24 January 2024
Crystal structure of the Kelch domain of human KLHL17
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