2xe0: Difference between revisions

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==Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus==
==Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus==
<StructureSection load='2xe0' size='340' side='right' caption='[[2xe0]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
<StructureSection load='2xe0' size='340' side='right'caption='[[2xe0]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2xe0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Chlre Chlre]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XE0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XE0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2xe0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XE0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XE0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PGO:S-1,2-PROPANEDIOL'>PGO</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.31&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xe0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xe0 OCA], [http://pdbe.org/2xe0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xe0 RCSB], [http://www.ebi.ac.uk/pdbsum/2xe0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xe0 ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PGO:S-1,2-PROPANEDIOL'>PGO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xe0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xe0 OCA], [https://pdbe.org/2xe0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xe0 RCSB], [https://www.ebi.ac.uk/pdbsum/2xe0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xe0 ProSAT]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Chlre]]
[[Category: Chlamydomonas reinhardtii]]
[[Category: Abramo, M D]]
[[Category: Homo sapiens]]
[[Category: Alibes, A]]
[[Category: Large Structures]]
[[Category: Blanco, F J]]
[[Category: Alibes A]]
[[Category: Chion-Sotine, I]]
[[Category: Blanco FJ]]
[[Category: Coloma, J]]
[[Category: Chion-Sotine I]]
[[Category: Daboussi, F]]
[[Category: Coloma J]]
[[Category: Duchateau, P]]
[[Category: D'Abramo M]]
[[Category: Gervasio, F L]]
[[Category: Daboussi F]]
[[Category: Grizot, S]]
[[Category: Duchateau P]]
[[Category: Marenchino, M]]
[[Category: Gervasio FL]]
[[Category: Merino, N]]
[[Category: Grizot S]]
[[Category: Montoya, G]]
[[Category: Marenchino M]]
[[Category: Munoz, I G]]
[[Category: Merino N]]
[[Category: Paques, F]]
[[Category: Montoya G]]
[[Category: Prieto, J]]
[[Category: Munoz IG]]
[[Category: Redondo, P]]
[[Category: Paques F]]
[[Category: Serrano, L]]
[[Category: Prieto J]]
[[Category: Smith, J]]
[[Category: Redondo P]]
[[Category: Stricher, F]]
[[Category: Serrano L]]
[[Category: Subramanian, S]]
[[Category: Smith J]]
[[Category: Villate, M]]
[[Category: Stricher F]]
[[Category: Dna binding protein]]
[[Category: Subramanian S]]
[[Category: Dna binding protein-dna complex]]
[[Category: Villate M]]
[[Category: Double-strand break]]
[[Category: Homing endonuclease]]
[[Category: Homologous recombination]]
[[Category: Human rag1 gene]]
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