6iie: Difference between revisions
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==Crystal structure of human diacylglycerol kinase alpha EF-hand domains bound to Ca2+== | |||
<StructureSection load='6iie' size='340' side='right'caption='[[6iie]], [[Resolution|resolution]] 2.14Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6iie]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IIE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IIE FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.142Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6iie FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6iie OCA], [https://pdbe.org/6iie PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6iie RCSB], [https://www.ebi.ac.uk/pdbsum/6iie PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6iie ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/DGKA_HUMAN DGKA_HUMAN] Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity. | |||
==See Also== | |||
*[[Diacylglycerol kinase 3D structures|Diacylglycerol kinase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Iwamoto T]] | |||
[[Category: Murata T]] | |||
[[Category: Sakamoto T]] | |||
[[Category: Sakane F]] | |||
[[Category: Suzuki K]] | |||
[[Category: Takahashi D]] | |||
Latest revision as of 10:33, 27 March 2024
Crystal structure of human diacylglycerol kinase alpha EF-hand domains bound to Ca2+
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