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[[Image:2qz8.jpg|left|200px]]


{{Structure
==Crystal structure of Mycobacterium tuberculosis Leucine response regulatory protein (LrpA)==
|PDB= 2qz8 |SIZE=350|CAPTION= <scene name='initialview01'>2qz8</scene>, resolution 2.16&Aring;
<StructureSection load='2qz8' size='340' side='right'caption='[[2qz8]], [[Resolution|resolution]] 2.16&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[2qz8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QZ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QZ8 FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.16&#8491;</td></tr>
|GENE= lrp, MT3390, Rv3291c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 Mycobacterium tuberculosis H37Rv])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qz8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qz8 OCA], [https://pdbe.org/2qz8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qz8 RCSB], [https://www.ebi.ac.uk/pdbsum/2qz8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qz8 ProSAT]</span></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=smart00344 HTH_ASNC], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1522 Lrp]</span>
</table>
|RELATEDENTRY=[[2qyd|2QYD]]
== Function ==
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qz8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qz8 OCA], [http://www.ebi.ac.uk/pdbsum/2qz8 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2qz8 RCSB]</span>
[https://www.uniprot.org/uniprot/P96896_MYCTO P96896_MYCTO]  
}}
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
'''Crystal structure of Mycobacterium tuberculosis Leucine response regulatory protein (LrpA)'''
Check<jmol>
 
  <jmolCheckbox>
 
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qz/2qz8_consurf.spt"</scriptWhenChecked>
==About this Structure==
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
2QZ8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QZ8 OCA].
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Mycobacterium tuberculosis h37rv]]
  </jmolCheckbox>
[[Category: Single protein]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qz8 ConSurf].
[[Category: Gokulan, K.]]
<div style="clear:both"></div>
[[Category: Ioerger, T.]]
__TOC__
[[Category: Jr., W R.Jacobs.]]
</StructureSection>
[[Category: Manchi, C M.R.]]
[[Category: Large Structures]]
[[Category: Sacchettini, J C.]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: TBSGC, TB Structural Genomics Consortium.]]
[[Category: Gokulan K]]
[[Category: dna-binding]]
[[Category: Ioerger T]]
[[Category: global transcriptional regulator]]
[[Category: Jacobs Jr WR]]
[[Category: hth motif]]
[[Category: Manchi CMR]]
[[Category: leucine responsive regulatory protein]]
[[Category: Sacchettini JC]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: structural genomic]]
[[Category: tb structural genomics consortium]]
[[Category: tbsgc]]
[[Category: transcription regulation]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:54:54 2008''

Latest revision as of 09:18, 21 February 2024

Crystal structure of Mycobacterium tuberculosis Leucine response regulatory protein (LrpA)

2qz8, resolution 2.16Å

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