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==Structure of the Bacillus subtilis prophage dUTPase, YosS==
==Structure of the Bacillus subtilis prophage dUTPase, YosS==
<StructureSection load='2xx6' size='340' side='right' caption='[[2xx6]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
<StructureSection load='2xx6' size='340' side='right'caption='[[2xx6]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2xx6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XX6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XX6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2xx6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XX6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XX6 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2baz|2baz]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.74&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dUTP_diphosphatase dUTP diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.23 3.6.1.23] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xx6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xx6 OCA], [https://pdbe.org/2xx6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xx6 RCSB], [https://www.ebi.ac.uk/pdbsum/2xx6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xx6 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xx6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xx6 OCA], [http://pdbe.org/2xx6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xx6 RCSB], [http://www.ebi.ac.uk/pdbsum/2xx6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xx6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/YOSS_BACSU YOSS_BACSU]] This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.  
[https://www.uniprot.org/uniprot/YOSS_BACSU YOSS_BACSU] This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Deoxyuridine 5'-triphosphate nucleotidohydrolase|Deoxyuridine 5'-triphosphate nucleotidohydrolase]]
*[[DUTPase 3D structures|DUTPase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Vibrio subtilis ehrenberg 1835]]
[[Category: Bacillus subtilis]]
[[Category: DUTP diphosphatase]]
[[Category: Large Structures]]
[[Category: Fogg, M J]]
[[Category: Fogg MJ]]
[[Category: Garcia-Nafria, J]]
[[Category: Garcia-Nafria J]]
[[Category: Harkiolaki, M]]
[[Category: Harkiolaki M]]
[[Category: Persson, R]]
[[Category: Persson R]]
[[Category: Wilson, K S]]
[[Category: Wilson KS]]
[[Category: Hydrolase]]
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