2xur: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
 
(2 intermediate revisions by the same user not shown)
Line 1: Line 1:


==The G157C mutation in the Escherichia coli sliding clamp specifically affects initiation of replication==
==The G157C mutation in the Escherichia coli sliding clamp specifically affects initiation of replication==
<StructureSection load='2xur' size='340' side='right' caption='[[2xur]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='2xur' size='340' side='right'caption='[[2xur]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2xur]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XUR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XUR FirstGlance]. <br>
<table><tr><td colspan='2'>[[2xur]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XUR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XUR FirstGlance]. <br>
</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xur FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xur OCA], [http://pdbe.org/2xur PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xur RCSB], [http://www.ebi.ac.uk/pdbsum/2xur PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xur ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xur FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xur OCA], [https://pdbe.org/2xur PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xur RCSB], [https://www.ebi.ac.uk/pdbsum/2xur PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xur ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DPO3B_ECOLI DPO3B_ECOLI]] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA.  
[https://www.uniprot.org/uniprot/DPO3B_ECOLI DPO3B_ECOLI] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 20: Line 20:


==See Also==
==See Also==
*[[DNA polymerase|DNA polymerase]]
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: DNA-directed DNA polymerase]]
[[Category: Large Structures]]
[[Category: Bjoras, M]]
[[Category: Bjoras M]]
[[Category: Dalhus, B]]
[[Category: Dalhus B]]
[[Category: Flaatten, I]]
[[Category: Flaatten I]]
[[Category: Johnsen, L]]
[[Category: Johnsen L]]
[[Category: Morigen]]
[[Category: Morigen]]
[[Category: Skarstad, K]]
[[Category: Skarstad K]]
[[Category: Waldminghaus, T]]
[[Category: Waldminghaus T]]
[[Category: Dna-directed dna polymerase]]
[[Category: Replication]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/2xur"