Main Page

ISSN 2310-6301 As life is more than 2D, Proteopedia helps to bridge the gap between 3D structure and function of biomacromolecules. Proteopedia presents this information in a user-friendly way as a collaborative & free 3D-encyclopedia of proteins & other biomolecules.
Selected Research Pages	In Journals	Education
Coronavirus Spike Protein Membrane Fusion by Eric Martz SARS-CoV-2 spike protein "spears" the host membrane with a fusion peptide and drags the virus envelope membrane transmembrane domain close to the host membrane, initiating fusion. This moves the virus RNA genome into the host cell, initiating infection. >>> Visit this page >>>	Geobacter nanowire structure surprise. F Wang, Y Gu, JP O'Brien, SM Yi, SE Yalcin, V Srikanth, C Shen, D Vu, NL Ing, AI Hochbaum, EH Egelman, NS Malvankar. Cell 2019 doi: 10.1016/j.cell.2019.03.029 Bacteria living in anaerobic environments (no oxygen) need alternative electron acceptors in order to get energy from their food. An acceptor abundant in the earth's crust is red iron oxide ("rust"), which gets reduced to black iron oxide (magnetite). Many bacteria, such as Geobacter, get their metabolic energy by transferring electrons to acceptors that are multiple cell diameters distant, using protein nanowires. These were long thought to be pili. But when the structure of the nanowires was solved in 2019, to everyone's surprise, they turned out to be unprecedented linear polymers of multi-heme cytochromes. The hemes form an electrically conductive chain in the cores of these nanowires. >>> Visit I3DC Interactive Visualizations >>>	Eastern Equine Encephalitis virus Although only a few people in the USA get Eastern Equine Encephalitis every year, the fatality rate is 30%, and many survivors have ongoing neurological problems. The virus is transmitted by mosquitoes from animals, especially birds, to humans. This RNA virus has a complicated capsid (a slab of which is shown) composed of protein shells with an enclosed lipid bilayer. The structures of virus capsids can be explored using free FirstGlance in Jmol. >>> Visit I3DC Interactive Visualizations >>>
How to add content to Proteopedia Video Guides Who knows ...	About Interactive 3D Complements - I3DCs List of I3DCs How to get an I3DC for your paper	Teaching strategies using Proteopedia Examples of pages for teaching How to add content to Proteopedia
About Contact Hot News Table of Contents Structure Index Help

Proteopedia Page Contributors and Editors (what is this?)

Jaime Prilusky, Joel L. Sussman, Angel Herraez