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[[Image:2tbv.gif|left|200px]]


{{Structure
==STRUCTURE OF TOMATO BUSHY STUNT VIRUS. V. COAT PROTEIN SEQUENCE DETERMINATION AND ITS STRUCTURAL IMPLICATIONS==
|PDB= 2tbv |SIZE=350|CAPTION= <scene name='initialview01'>2tbv</scene>, resolution 2.90&Aring;
<StructureSection load='2tbv' size='340' side='right'caption='[[2tbv]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>
<table><tr><td colspan='2'>[[2tbv]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Tomato_bushy_stunt_virus Tomato bushy stunt virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2TBV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2TBV FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2tbv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2tbv OCA], [https://pdbe.org/2tbv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2tbv RCSB], [https://www.ebi.ac.uk/pdbsum/2tbv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2tbv ProSAT]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2tbv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2tbv OCA], [http://www.ebi.ac.uk/pdbsum/2tbv PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2tbv RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/CAPSD_TBSVB CAPSD_TBSVB] Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 32-35 nm in diameter, and consisting of 180 capsid proteins.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tb/2tbv_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2tbv ConSurf].
<div style="clear:both"></div>


'''STRUCTURE OF TOMATO BUSHY STUNT VIRUS. V. COAT PROTEIN SEQUENCE DETERMINATION AND ITS STRUCTURAL IMPLICATIONS'''
==See Also==
 
*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
 
__TOC__
==Overview==
</StructureSection>
We report the chemically determined sequence of most of the polypeptide chain of the coat protein of tomato bushy stunt virus. Peptide locations have been determined by comparison with the high-resolution electron density map from X-ray crystallographic analysis as well as by conventional chemical overlaps. Three small gaps remain in the 387-residue sequence. Positively charged side-chains are concentrated in the N-terminal part of the polypeptide (the R domain) as well as on inward-facing surfaces of the S domain. There is homology of S-domain sequences with structurally corresponding residues in southern bean mosaic virus.
[[Category: Large Structures]]
 
==About this Structure==
2TBV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Tomato_bushy_stunt_virus Tomato bushy stunt virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2TBV OCA].
 
==Reference==
Structure of tomato bushy stunt virus. V. Coat protein sequence determination and its structural implications., Hopper P, Harrison SC, Sauer RT, J Mol Biol. 1984 Aug 25;177(4):701-13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/6481803 6481803]
[[Category: Single protein]]
[[Category: Tomato bushy stunt virus]]
[[Category: Tomato bushy stunt virus]]
[[Category: Harrison, S C.]]
[[Category: Harrison SC]]
[[Category: icosahedral virus]]
[[Category: virus]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:03:29 2008''