2tgp: Difference between revisions

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[[Image:2tgp.jpg|left|200px]]


{{Structure
==THE GEOMETRY OF THE REACTIVE SITE AND OF THE PEPTIDE GROUPS IN TRYPSIN, TRYPSINOGEN AND ITS COMPLEXES WITH INHIBITORS==
|PDB= 2tgp |SIZE=350|CAPTION= <scene name='initialview01'>2tgp</scene>, resolution 1.9&Aring;
<StructureSection load='2tgp' size='340' side='right'caption='[[2tgp]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
<table><tr><td colspan='2'>[[2tgp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1tgp 1tgp]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2TGP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2TGP FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2tgp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2tgp OCA], [https://pdbe.org/2tgp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2tgp RCSB], [https://www.ebi.ac.uk/pdbsum/2tgp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2tgp ProSAT]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2tgp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2tgp OCA], [http://www.ebi.ac.uk/pdbsum/2tgp PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2tgp RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/TRY1_BOVIN TRY1_BOVIN]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tg/2tgp_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2tgp ConSurf].
<div style="clear:both"></div>


'''THE GEOMETRY OF THE REACTIVE SITE AND OF THE PEPTIDE GROUPS IN TRYPSIN, TRYPSINOGEN AND ITS COMPLEXES WITH INHIBITORS'''
==See Also==
 
*[[BPTI 3D structures|BPTI 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2TGP is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. This structure supersedes the now removed PDB entry 1TGP. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2TGP OCA].
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Protein complex]]
[[Category: Large Structures]]
[[Category: Bode, W.]]
[[Category: Bode W]]
[[Category: Deisenhofer, J.]]
[[Category: Deisenhofer J]]
[[Category: Huber, R.]]
[[Category: Huber R]]
[[Category: Schwager, P.]]
[[Category: Schwager P]]
[[Category: complex (proteinase/inhibitor)]]
 
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