3a6h: Difference between revisions
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==W154A mutant creatininase== | ==W154A mutant creatininase== | ||
<StructureSection load='3a6h' size='340' side='right' caption='[[3a6h]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='3a6h' size='340' side='right'caption='[[3a6h]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3a6h]] is a 6 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3a6h]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A6H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3A6H FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
< | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3a6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a6h OCA], [https://pdbe.org/3a6h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3a6h RCSB], [https://www.ebi.ac.uk/pdbsum/3a6h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3a6h ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/CRNA_PSEPU CRNA_PSEPU] Cyclic amidohydrolase that catalyzes the reversible conversion of creatinine to creatine. Is also active toward glycocyamidine, though the reaction rate is very low, but it is completely inert toward hydantoin and its derivatives.<ref>PMID:500580</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Pseudomonas putida]] | ||
[[Category: Ito | [[Category: Ito K]] | ||
[[Category: Nakajima | [[Category: Nakajima Y]] | ||
[[Category: Yamashita | [[Category: Yamashita K]] | ||
[[Category: Yoshimoto | [[Category: Yoshimoto T]] | ||