CD55: Difference between revisions

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New page: <StructureSection load='1ojv' size='340' side='right' caption='Caption for this structure' scene=''> <ref>PMID:21638687</ref> to the rescue. == Function == '''CD55''' or decay-accelerat...
 
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<StructureSection load='1ojv' size='340' side='right' caption='Human CD55 short concensus repeat (SCR) domains dimer complex with sulfate, acetate and glycerol (PDB code [[1ojv]])' scene=''>
<StructureSection load='1ojv' size='340' side='right' caption='Caption for this structure' scene=''>
<ref>PMID:21638687</ref> to the rescue.


== Function ==
== Function ==


'''CD55''' or decay-accelerating factor (DAF) serves as an inhibitor of the complement system.  It is broadly expressed in malignant tumors<ref>PMID:16784816</ref>.
'''CD55''' or '''complement decay-accelerating factor''' (DAF) serves as an inhibitor of the complement system.  It is broadly expressed in malignant tumors<ref>PMID:16784816</ref>.


== Disease ==
== Disease ==
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== Relevance ==
== Relevance ==


CD55 is involved in promotion of tumorigenesis, decrease of complement mediated tumor cell lysis, evasion of apoptosis, cell motility and metastais.  CD55 is included in diagnostic or therapeutic studies.
CD55 is involved in promotion of tumorigenesis, decrease of complement mediated tumor cell lysis, evasion of apoptosis, cell motility and metastasis.  CD55 is included in diagnostic or therapeutic studies.
 
== Structural highlights ==




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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}


[[3j24]] - hCD55 - human - Cryo EM<br />
[[3j24]], [[2qzd]], [[2qzf]], [[2qzh]] - hCD55 - human - Cryo EM<br />
[[1ojv]], [[1ojw]], [[1ojy]], [[1ok1]], [[1ok2]], [[1ok3]], [[1ok9]] - hCD55<br />
[[1ojv]], [[1ojw]], [[1ojy]], [[1ok1]], [[1ok2]], [[1ok3]], [[1ok9]] - hCD55<br />
[[1nwv]] - hCD55 - NMR<br />
[[1nwv]] - hCD55 - NMR<br />
[[1uot]], [[1h03]], [[1h2p]], [[1h2q]], [[1h04]] - hCD55 domains 3,4<br />
[[1uot]], [[1h03]], [[1h2p]], [[1h2q]], [[1h04]] - hCD55 domains 3,4<br />
[[3iyp]], [[2c8i]], [[1upn]] - hCD55 + echovirus - Cryo EM<br />
[[1m11]], [[3iyp]], [[2c8i]], [[1upn]], [[6ilj]], [[6ilk]], [[6la5]], [[6lao]], [[7c9w]], [[8b8r]], [[8b9f]] - hCD55 + echovirus - Cryo EM<br />
[[7vy5]], [[7vy6]] - hCD55 + coxsakievirus - Cryo EM<br />
[[5foa]] - hCD55 + complement C3 + complement C3B<br />
[[5foa]] - hCD55 + complement C3 + complement C3B<br />
[[7do4]] - hCD55 + CD97<br />
== References ==
== References ==
<references/>
<references/>


[[Category:Topic Page]]
[[Category:Topic Page]]

Latest revision as of 08:45, 20 January 2025

Human CD55 short concensus repeat (SCR) domains dimer complex with sulfate, acetate and glycerol (PDB code 1ojv)

Drag the structure with the mouse to rotate

3D structures of CD55

Updated on 20-January-2025

3j24, 2qzd, 2qzf, 2qzh - hCD55 - human - Cryo EM
1ojv, 1ojw, 1ojy, 1ok1, 1ok2, 1ok3, 1ok9 - hCD55
1nwv - hCD55 - NMR
1uot, 1h03, 1h2p, 1h2q, 1h04 - hCD55 domains 3,4
1m11, 3iyp, 2c8i, 1upn, 6ilj, 6ilk, 6la5, 6lao, 7c9w, 8b8r, 8b9f - hCD55 + echovirus - Cryo EM
7vy5, 7vy6 - hCD55 + coxsakievirus - Cryo EM
5foa - hCD55 + complement C3 + complement C3B
7do4 - hCD55 + CD97

References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel