CD55: Difference between revisions
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Michal Harel (talk | contribs) New page: <StructureSection load='1ojv' size='340' side='right' caption='Caption for this structure' scene=''> <ref>PMID:21638687</ref> to the rescue. == Function == '''CD55''' or decay-accelerat... |
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<StructureSection load='1ojv' size='340' side='right' caption='Human CD55 short concensus repeat (SCR) domains dimer complex with sulfate, acetate and glycerol (PDB code [[1ojv]])' scene=''> | |||
<StructureSection load='1ojv' size='340' side='right' caption=' | |||
== Function == | == Function == | ||
'''CD55''' or decay-accelerating factor (DAF) serves as an inhibitor of the complement system. It is broadly expressed in malignant tumors<ref>PMID:16784816</ref>. | '''CD55''' or '''complement decay-accelerating factor''' (DAF) serves as an inhibitor of the complement system. It is broadly expressed in malignant tumors<ref>PMID:16784816</ref>. | ||
== Disease == | == Disease == | ||
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== Relevance == | == Relevance == | ||
CD55 is involved in promotion of tumorigenesis, decrease of complement mediated tumor cell lysis, evasion of apoptosis, cell motility and | CD55 is involved in promotion of tumorigenesis, decrease of complement mediated tumor cell lysis, evasion of apoptosis, cell motility and metastasis. CD55 is included in diagnostic or therapeutic studies. | ||
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
[[3j24]] - hCD55 - human - Cryo EM<br /> | [[3j24]], [[2qzd]], [[2qzf]], [[2qzh]] - hCD55 - human - Cryo EM<br /> | ||
[[1ojv]], [[1ojw]], [[1ojy]], [[1ok1]], [[1ok2]], [[1ok3]], [[1ok9]] - hCD55<br /> | [[1ojv]], [[1ojw]], [[1ojy]], [[1ok1]], [[1ok2]], [[1ok3]], [[1ok9]] - hCD55<br /> | ||
[[1nwv]] - hCD55 - NMR<br /> | [[1nwv]] - hCD55 - NMR<br /> | ||
[[1uot]], [[1h03]], [[1h2p]], [[1h2q]], [[1h04]] - hCD55 domains 3,4<br /> | [[1uot]], [[1h03]], [[1h2p]], [[1h2q]], [[1h04]] - hCD55 domains 3,4<br /> | ||
[[3iyp]], [[2c8i]], [[1upn]] - hCD55 + echovirus - Cryo EM<br /> | [[1m11]], [[3iyp]], [[2c8i]], [[1upn]], [[6ilj]], [[6ilk]], [[6la5]], [[6lao]], [[7c9w]], [[8b8r]], [[8b9f]] - hCD55 + echovirus - Cryo EM<br /> | ||
[[7vy5]], [[7vy6]] - hCD55 + coxsakievirus - Cryo EM<br /> | |||
[[5foa]] - hCD55 + complement C3 + complement C3B<br /> | [[5foa]] - hCD55 + complement C3 + complement C3B<br /> | ||
[[7do4]] - hCD55 + CD97<br /> | |||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Latest revision as of 08:45, 20 January 2025
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3D structures of CD55
Updated on 20-January-2025
3j24, 2qzd, 2qzf, 2qzh - hCD55 - human - Cryo EM
1ojv, 1ojw, 1ojy, 1ok1, 1ok2, 1ok3, 1ok9 - hCD55
1nwv - hCD55 - NMR
1uot, 1h03, 1h2p, 1h2q, 1h04 - hCD55 domains 3,4
1m11, 3iyp, 2c8i, 1upn, 6ilj, 6ilk, 6la5, 6lao, 7c9w, 8b8r, 8b9f - hCD55 + echovirus - Cryo EM
7vy5, 7vy6 - hCD55 + coxsakievirus - Cryo EM
5foa - hCD55 + complement C3 + complement C3B
7do4 - hCD55 + CD97