6ioz: Difference between revisions
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New page: '''Unreleased structure''' The entry 6ioz is ON HOLD Authors: Kim, H., Kim, D., Hong, J., Lee, K., Seo, J., Oh, B.H. Description: Structural insights of idursulfase beta [[Category: Un... |
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The entry | ==Structural insights of idursulfase beta== | ||
<StructureSection load='6ioz' size='340' side='right'caption='[[6ioz]], [[Resolution|resolution]] 3.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6ioz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IOZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IOZ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALS:(3S)-3-(SULFOOXY)-L-SERINE'>ALS</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ioz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ioz OCA], [https://pdbe.org/6ioz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ioz RCSB], [https://www.ebi.ac.uk/pdbsum/6ioz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ioz ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/IDS_HUMAN IDS_HUMAN] Mucopolysaccharidosis type 2, attenuated form;Mucopolysaccharidosis type 2, severe form. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/IDS_HUMAN IDS_HUMAN] Required for the lysosomal degradation of heparan sulfate and dermatan sulfate. | |||
==See Also== | |||
*[[Sulfatase 3D structures|Sulfatase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Hong J]] | ||
[[Category: | [[Category: Kim D]] | ||
[[Category: Oh | [[Category: Kim H]] | ||
[[Category: | [[Category: Lee K]] | ||
[[Category: Oh BH]] | |||
[[Category: Seo J]] | |||
Latest revision as of 09:48, 22 November 2023
Structural insights of idursulfase beta
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