3apw: Difference between revisions
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==Crystal structure of the A variant of human alpha1-acid glycoprotein and disopyramide complex== | ==Crystal structure of the A variant of human alpha1-acid glycoprotein and disopyramide complex== | ||
<StructureSection load='3apw' size='340' side='right' caption='[[3apw]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='3apw' size='340' side='right'caption='[[3apw]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3apw]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3apw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3APW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3APW FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DP0:DISOPYRAMIDE'>DP0</scene></td></tr> | |||
<tr id=' | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3apw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3apw OCA], [https://pdbe.org/3apw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3apw RCSB], [https://www.ebi.ac.uk/pdbsum/3apw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3apw ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/A1AG2_HUMAN A1AG2_HUMAN] Functions as transport protein in the blood stream. Binds various hydrophobic ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability. Appears to function in modulating the activity of the immune system during the acute-phase reaction.<ref>PMID:21349832</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Curry | [[Category: Large Structures]] | ||
[[Category: Fukunaga | [[Category: Curry S]] | ||
[[Category: Izumi | [[Category: Fukunaga N]] | ||
[[Category: Maruyama | [[Category: Izumi M]] | ||
[[Category: Nakamura | [[Category: Maruyama T]] | ||
[[Category: Nishi | [[Category: Nakamura T]] | ||
[[Category: Ono | [[Category: Nishi K]] | ||
[[Category: Otagiri | [[Category: Ono T]] | ||
[[Category: Suenaga | [[Category: Otagiri M]] | ||
[[Category: Watanabe | [[Category: Suenaga A]] | ||
[[Category: Yamagata | [[Category: Watanabe H]] | ||
[[Category: Yamagata Y]] | |||
