6n0j: Difference between revisions

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~~'''Unreleased structure'''~~

The ~~entry~~ 6n0j is ~~ON HOLD~~

==The complex of CCG-222740 bound to pirin==

== Structural highlights ==

<table><tr><td colspan='2'>[[6n0j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N0J OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=6N0J FirstGlance].

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.79Å</td></tr>

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=K8S:(3S)-N-(4-chlorophenyl)-5,5-difluoro-1-[3-(furan-2-yl)benzene-1-carbonyl]piperidine-3-carboxamide'>K8S</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=6n0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n0j OCA], [https://pdbe.org/6n0j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6n0j RCSB], [https://www.ebi.ac.uk/pdbsum/6n0j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6n0j ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/PIR_HUMAN PIR_HUMAN] Possible transcriptional coregulator. May contribute to the regulation of cellular processes via its interaction with BCL3. May be required for efficient terminal myeloid maturation of hematopoietic cells. May play a role in the regulation of cell migration. May promote apoptosis when overexpressed. Has quercetin 2,3-dioxygenase activity (in vitro).<ref>PMID:9079676</ref> <ref>PMID:17288615</ref> <ref>PMID:20010624</ref> <ref>PMID:20711196</ref>

~~Authors~~:

==See Also==

*[[Dioxygenase 3D structures|Dioxygenase 3D structures]]

~~Description~~:

== References ==

[[Category: ~~Unreleased Structures~~]]

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Jin X]]

[[Category: Lisabeth EM]]

[[Category: Neubig R]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6n0j is ON HOLD
+==The complex of CCG-222740 bound to pirin==
+<StructureSection load='6n0j' size='340' side='right'caption='[[6n0j]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6n0j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N0J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6N0J FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.79&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=K8S:(3S)-N-(4-chlorophenyl)-5,5-difluoro-1-[3-(furan-2-yl)benzene-1-carbonyl]piperidine-3-carboxamide'>K8S</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6n0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n0j OCA], [https://pdbe.org/6n0j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6n0j RCSB], [https://www.ebi.ac.uk/pdbsum/6n0j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6n0j ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PIR_HUMAN PIR_HUMAN] Possible transcriptional coregulator. May contribute to the regulation of cellular processes via its interaction with BCL3. May be required for efficient terminal myeloid maturation of hematopoietic cells. May play a role in the regulation of cell migration. May promote apoptosis when overexpressed. Has quercetin 2,3-dioxygenase activity (in vitro).<ref>PMID:9079676</ref> <ref>PMID:17288615</ref> <ref>PMID:20010624</ref> <ref>PMID:20711196</ref>
-Authors:
+==See Also==
+*[[Dioxygenase 3D structures|Dioxygenase 3D structures]]
-Description:
+== References ==
-[[Category: Unreleased Structures]]
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Jin X]]
+[[Category: Lisabeth EM]]
+[[Category: Neubig R]]