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==NMR Structural and biophysical functional analysis of intracellular loop 5 of the NHE1 isoform of the Na+/H+ exchanger.==
==NMR Structural and biophysical functional analysis of intracellular loop 5 of the NHE1 isoform of the Na+/H+ exchanger.==
<StructureSection load='6bjf' size='340' side='right' caption='[[6bjf]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='6bjf' size='340' side='right'caption='[[6bjf]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6bjf]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BJF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BJF FirstGlance]. <br>
<table><tr><td colspan='2'>[[6bjf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BJF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BJF FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bjf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bjf OCA], [http://pdbe.org/6bjf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bjf RCSB], [http://www.ebi.ac.uk/pdbsum/6bjf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bjf ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bjf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bjf OCA], [https://pdbe.org/6bjf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bjf RCSB], [https://www.ebi.ac.uk/pdbsum/6bjf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bjf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SL9A1_HUMAN SL9A1_HUMAN] Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.<ref>PMID:8901634</ref> <ref>PMID:11350981</ref> <ref>PMID:15035633</ref>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Fliegel, L]]
[[Category: Homo sapiens]]
[[Category: McKay, R]]
[[Category: Large Structures]]
[[Category: Towle, K]]
[[Category: Fliegel L]]
[[Category: Wong, K]]
[[Category: McKay R]]
[[Category: Membrane protein]]
[[Category: Towle K]]
[[Category: Structure from cyana 2 1]]
[[Category: Wong K]]

Latest revision as of 07:29, 1 May 2024

NMR Structural and biophysical functional analysis of intracellular loop 5 of the NHE1 isoform of the Na+/H+ exchanger.

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