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==Crystal structure of methyltransferase involved in cell division from thermoplasma volcanicum gss1==
==Crystal structure of methyltransferase involved in cell division from thermoplasma volcanicum gss1==
<StructureSection load='3dou' size='340' side='right' caption='[[3dou]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
<StructureSection load='3dou' size='340' side='right'caption='[[3dou]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3dou]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_51530 Atcc 51530]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DOU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3DOU FirstGlance]. <br>
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DOU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DOU FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rrmJ, TV0292, TVG0303954 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=50339 ATCC 51530])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dou FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dou OCA], [https://pdbe.org/3dou PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dou RCSB], [https://www.ebi.ac.uk/pdbsum/3dou PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dou ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/3dou TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dou FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dou OCA], [http://pdbe.org/3dou PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3dou RCSB], [http://www.ebi.ac.uk/pdbsum/3dou PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3dou ProSAT], [http://www.topsan.org/Proteins/NYSGXRC/3dou TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/RLME_THEVO RLME_THEVO]] Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.[HAMAP-Rule:MF_01547]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/do/3dou_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/do/3dou_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 51530]]
[[Category: Large Structures]]
[[Category: Almo, S C]]
[[Category: Almo SC]]
[[Category: Bain, K]]
[[Category: Bain K]]
[[Category: Burley, S K]]
[[Category: Burley SK]]
[[Category: Dickey, M]]
[[Category: Dickey M]]
[[Category: Hu, S]]
[[Category: Hu S]]
[[Category: Structural genomic]]
[[Category: Ozyurt S]]
[[Category: Ozyurt, S]]
[[Category: Patskovsky Y]]
[[Category: Patskovsky, Y]]
[[Category: Sauder JM]]
[[Category: Sauder, J M]]
[[Category: Wasserman S]]
[[Category: Wasserman, S]]
[[Category: Cell division]]
[[Category: Cytoplasm]]
[[Category: Methyltransferase]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
[[Category: PSI, Protein structure initiative]]
[[Category: Rrna processing]]
[[Category: Transferase]]

Latest revision as of 09:00, 30 October 2024

Crystal structure of methyltransferase involved in cell division from thermoplasma volcanicum gss1

3dou, resolution 1.45Å

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