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==Crystal structure of anti-Zika antibody Z021 bound to Zika virus envelope protein DIII==
==Crystal structure of anti-Zika antibody Z021 bound to Zika virus envelope protein DIII==
<StructureSection load='6dfi' size='340' side='right' caption='[[6dfi]], [[Resolution|resolution]] 2.48&Aring;' scene=''>
<StructureSection load='6dfi' size='340' side='right'caption='[[6dfi]], [[Resolution|resolution]] 2.48&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6dfi]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Zikv Zikv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DFI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DFI FirstGlance]. <br>
<table><tr><td colspan='2'>[[6dfi]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Zika_virus Zika virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DFI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6DFI FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dfi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dfi OCA], [http://pdbe.org/6dfi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dfi RCSB], [http://www.ebi.ac.uk/pdbsum/6dfi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dfi ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.48&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6dfi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dfi OCA], [https://pdbe.org/6dfi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6dfi RCSB], [https://www.ebi.ac.uk/pdbsum/6dfi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6dfi ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A0U3FSM8_ZIKV A0A0U3FSM8_ZIKV] Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[ARBA:ARBA00003504]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6dfi" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6dfi" style="background-color:#fffaf0;"></div>
==See Also==
*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
*[[3D structures of human antibody|3D structures of human antibody]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Zikv]]
[[Category: Large Structures]]
[[Category: Bjorkman, P J]]
[[Category: Zika virus]]
[[Category: Keeffe, J R]]
[[Category: Bjorkman PJ]]
[[Category: Antibody]]
[[Category: Keeffe JR]]
[[Category: Dengue]]
[[Category: Fab]]
[[Category: Immune system]]
[[Category: Neutralizing]]
[[Category: Recurrent]]
[[Category: Zika]]
Retrieved from "https://proteopedia.org/6dfi"