6i5u: Difference between revisions

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~~'''Unreleased structure'''~~

~~The entry~~ 6i5u is ~~ON HOLD~~

==Cryo-EM informed directed evolution of Nitrilase 4 leads to a change in quaternary structure.==

~~Authors~~: ~~Mulelu~~, A.E., ~~Woodward~~, J.D.

== Structural highlights ==

<table><tr><td colspan='2'>[[6i5u]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I5U OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6I5U FirstGlance]. <br>

~~Description~~: ~~Cryo~~-~~EM informed directed evolution of Nitrilase 4 leads to a change~~ in ~~quaternary structure~~.

</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NIT4, At5g22300, MWD9.8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6i5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i5u OCA], [http://pdbe.org/6i5u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6i5u RCSB], [http://www.ebi.ac.uk/pdbsum/6i5u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6i5u ProSAT]</span></td></tr>

[[Category: Mulelu, A.E]]

</table>

[[Category: Woodward, J.D]]

== Function ==

[[http://www.uniprot.org/uniprot/NRL4_ARATH NRL4_ARATH]] Highly specific for beta-cyano-L-alanine (Ala(CN)). Low activity with 3-phenylpropionitrile (PPN) or allylcyanide and no activity with indole-3-acetonitrile. Not associated with auxin production but may be involved in cyanide detoxification.<ref>PMID:11060302</ref>

== References ==

__TOC__

</SX>

[[Category: Arath]]

[[Category: Large Structures]]

[[Category: Mulelu, A E]]

[[Category: Woodward, J D]]

[[Category: Beta-cyano-l-alanine hydrolase]]

[[Category: Cyanide detoxification]]

[[Category: Helical filament]]

[[Category: Hydrolase]]

[[Category: Nitrilase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6i5u is ON HOLD
+==Cryo-EM informed directed evolution of Nitrilase 4 leads to a change in quaternary structure.==
+<SX load='6i5u' size='340' side='right' viewer='molstar' caption='[[6i5u]], [[Resolution|resolution]] 3.90&Aring;' scene=''>
-Authors: Mulelu, A.E., Woodward, J.D.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6i5u]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I5U OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6I5U FirstGlance]. <br>
-Description: Cryo-EM informed directed evolution of Nitrilase 4 leads to a change in quaternary structure.
+</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NIT4, At5g22300, MWD9.8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6i5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i5u OCA], [http://pdbe.org/6i5u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6i5u RCSB], [http://www.ebi.ac.uk/pdbsum/6i5u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6i5u ProSAT]</span></td></tr>
-[[Category: Mulelu, A.E]]
+</table>
-[[Category: Woodward, J.D]]
+== Function ==
+[[http://www.uniprot.org/uniprot/NRL4_ARATH NRL4_ARATH]] Highly specific for beta-cyano-L-alanine (Ala(CN)). Low activity with 3-phenylpropionitrile (PPN) or allylcyanide and no activity with indole-3-acetonitrile. Not associated with auxin production but may be involved in cyanide detoxification.<ref>PMID:11060302</ref>
+== References ==
+<references/>
+__TOC__
+</SX>
+[[Category: Arath]]
+[[Category: Large Structures]]
+[[Category: Mulelu, A E]]
+[[Category: Woodward, J D]]
+[[Category: Beta-cyano-l-alanine hydrolase]]
+[[Category: Cyanide detoxification]]
+[[Category: Helical filament]]
+[[Category: Hydrolase]]
+[[Category: Nitrilase]]