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New page: '''Unreleased structure''' The entry 6is0 is ON HOLD Authors: Hirano, S., Nishimasu, H., Ishitani, R., Nureki, O. Description: Crystal structure of the zebrafish cap-specific adenosine...
 
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'''Unreleased structure'''


The entry 6is0 is ON HOLD
==Crystal structure of the zebrafish cap-specific adenosine methyltransferase bound to SAH and m7G-capped RNA==
 
<StructureSection load='6is0' size='340' side='right'caption='[[6is0]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
Authors: Hirano, S., Nishimasu, H., Ishitani, R., Nureki, O.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6is0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Danio_rerio Danio rerio] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IS0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IS0 FirstGlance]. <br>
Description: Crystal structure of the zebrafish cap-specific adenosine methyltransferase bound to SAH and m7G-capped RNA
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2M:2-O-METHYLADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>A2M</scene>, <scene name='pdbligand=B3P:2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>B3P</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=M7G:7N-METHYL-8-HYDROGUANOSINE-5-DIPHOSPHATE'>M7G</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
[[Category: Nureki, O]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6is0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6is0 OCA], [https://pdbe.org/6is0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6is0 RCSB], [https://www.ebi.ac.uk/pdbsum/6is0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6is0 ProSAT]</span></td></tr>
[[Category: Hirano, S]]
</table>
[[Category: Nishimasu, H]]
== Function ==
[[Category: Ishitani, R]]
[https://www.uniprot.org/uniprot/CAPAM_DANRE CAPAM_DANRE] Cap-specific adenosine methyltransferase that catalyzes formation of N(6),2'-O-dimethyladenosine cap (m6A(m)) by methylating the adenosine at the second transcribed position of capped mRNAs (PubMed:30467178).<ref>PMID:30467178</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Danio rerio]]
[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Hirano S]]
[[Category: Ishitani R]]
[[Category: Nishimasu H]]
[[Category: Nureki O]]
Retrieved from "https://proteopedia.org/6is0"