6n3e: Difference between revisions

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~~'''Unreleased structure'''~~

~~The entry~~ 6n3e is ~~ON HOLD~~

==Structure of HIV Tat-specific factor 1 U2AF Homology Motif bound to U2AF ligand motif 4==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6n3e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N3E OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=6N3E FirstGlance].

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.893Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=6n3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n3e OCA], [https://pdbe.org/6n3e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6n3e RCSB], [https://www.ebi.ac.uk/pdbsum/6n3e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6n3e ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/HTSF1_HUMAN HTSF1_HUMAN] Functions as a general transcription factor playing a role in the process of transcriptional elongation. May mediate the reciprocal stimulatory effect of splicing on transcriptional elongation. In case of infection by HIV-1, it is up-regulated by the HIV-1 proteins NEF and gp120, acts as a cofactor required for the Tat-enhanced transcription of the virus.<ref>PMID:10393184</ref> <ref>PMID:10454543</ref> <ref>PMID:10913173</ref> <ref>PMID:11420046</ref> <ref>PMID:11780068</ref> <ref>PMID:15905670</ref> <ref>PMID:8849451</ref> <ref>PMID:9765201</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Jenkins JL]]

[[Category: Kielkopf CL]]

[[Category: Loerch S]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6n3e is ON HOLD
+==Structure of HIV Tat-specific factor 1 U2AF Homology Motif bound to U2AF ligand motif 4==
+<StructureSection load='6n3e' size='340' side='right'caption='[[6n3e]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6n3e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N3E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6N3E FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.893&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6n3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n3e OCA], [https://pdbe.org/6n3e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6n3e RCSB], [https://www.ebi.ac.uk/pdbsum/6n3e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6n3e ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/HTSF1_HUMAN HTSF1_HUMAN] Functions as a general transcription factor playing a role in the process of transcriptional elongation. May mediate the reciprocal stimulatory effect of splicing on transcriptional elongation. In case of infection by HIV-1, it is up-regulated by the HIV-1 proteins NEF and gp120, acts as a cofactor required for the Tat-enhanced transcription of the virus.<ref>PMID:10393184</ref> <ref>PMID:10454543</ref> <ref>PMID:10913173</ref> <ref>PMID:11420046</ref> <ref>PMID:11780068</ref> <ref>PMID:15905670</ref> <ref>PMID:8849451</ref> <ref>PMID:9765201</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Jenkins JL]]
+[[Category: Kielkopf CL]]
+[[Category: Loerch S]]