2z0s: Difference between revisions

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[[Image:2z0s.jpg|left|200px]]


{{Structure
==Crystal structure of putative exosome complex RNA-binding protein==
|PDB= 2z0s |SIZE=350|CAPTION= <scene name='initialview01'>2z0s</scene>, resolution 3.20&Aring;
<StructureSection load='2z0s' size='340' side='right'caption='[[2z0s]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[2z0s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z0S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z0S FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
|GENE=  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z0s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z0s OCA], [https://pdbe.org/2z0s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z0s RCSB], [https://www.ebi.ac.uk/pdbsum/2z0s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z0s ProSAT], [https://www.topsan.org/Proteins/RSGI/2z0s TOPSAN]</span></td></tr>
|DOMAIN=
</table>
|RELATEDENTRY=
== Function ==
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z0s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z0s OCA], [http://www.ebi.ac.uk/pdbsum/2z0s PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2z0s RCSB]</span>
[https://www.uniprot.org/uniprot/RRP4_AERPE RRP4_AERPE] Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.[HAMAP-Rule:MF_00623]
}}
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
'''Crystal structure of putative exosome complex RNA-binding protein'''
Check<jmol>
 
  <jmolCheckbox>
 
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z0/2z0s_consurf.spt"</scriptWhenChecked>
==About this Structure==
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
2Z0S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z0S OCA].  
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z0s ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Aeropyrum pernix]]
[[Category: Aeropyrum pernix]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Kato-Murayama, M.]]
[[Category: Kato-Murayama M]]
[[Category: Murayama, K.]]
[[Category: Murayama K]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Shirouzu M]]
[[Category: Shirouzu, M.]]
[[Category: Takemoto C]]
[[Category: Takemoto, C.]]
[[Category: Terada T]]
[[Category: Terada, T.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: alpha/beta protein]]
[[Category: cytoplasm]]
[[Category: exosome]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rna binding protein]]
[[Category: rsgi]]
[[Category: structural genomic]]
 
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