2z1a: Difference between revisions

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[[Image:2z1a.jpg|left|200px]]


{{Structure
==Crystal structure of 5'-nucleotidase precursor from Thermus thermophilus HB8==
|PDB= 2z1a |SIZE=350|CAPTION= <scene name='initialview01'>2z1a</scene>, resolution 1.75&Aring;
<StructureSection load='2z1a' size='340' side='right'caption='[[2z1a]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=THM:THYMIDINE'>THM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
<table><tr><td colspan='2'>[[2z1a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z1A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z1A FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/5'-nucleotidase 5'-nucleotidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.5 3.1.3.5] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
|GENE=
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=THM:THYMIDINE'>THM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z1a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z1a OCA], [https://pdbe.org/2z1a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z1a RCSB], [https://www.ebi.ac.uk/pdbsum/2z1a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z1a ProSAT], [https://www.topsan.org/Proteins/RSGI/2z1a TOPSAN]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z1a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z1a OCA], [http://www.ebi.ac.uk/pdbsum/2z1a PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2z1a RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/Q5SIP1_THET8 Q5SIP1_THET8]
 
== Evolutionary Conservation ==
'''Crystal structure of 5'-nucleotidase precursor from Thermus thermophilus HB8'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z1/2z1a_consurf.spt"</scriptWhenChecked>
2Z1A is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z1A OCA].  
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: 5'-nucleotidase]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Single protein]]
  </jmolCheckbox>
[[Category: Thermus thermophilus]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z1a ConSurf].
[[Category: Kishishita, S.]]
<div style="clear:both"></div>
[[Category: Kuramitsu, S.]]
__TOC__
[[Category: Nakagawa, N.]]
</StructureSection>
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Large Structures]]
[[Category: Yokoyama, S.]]
[[Category: Thermus thermophilus HB8]]
[[Category: hydrolase]]
[[Category: Kishishita S]]
[[Category: metal-binding]]
[[Category: Kuramitsu S]]
[[Category: national project on protein structural and functional analyse]]
[[Category: Nakagawa N]]
[[Category: nppsfa]]
[[Category: Yokoyama S]]
[[Category: nucleotidase]]
[[Category: nucleotide-binding]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
 
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