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[[Image:2z1n.jpg|left|200px]]


{{Structure
==Crystal structure of APE0912 from Aeropyrum pernix K1==
|PDB= 2z1n |SIZE=350|CAPTION= <scene name='initialview01'>2z1n</scene>, resolution 1.80&Aring;
<StructureSection load='2z1n' size='340' side='right'caption='[[2z1n]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
|SITE= <scene name='pdbsite=AC1:Na+Binding+Site+For+Residue+A+1001'>AC1</scene> and <scene name='pdbsite=AC2:Na+Binding+Site+For+Residue+A+2001'>AC2</scene>
== Structural highlights ==
|LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>
<table><tr><td colspan='2'>[[2z1n]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aeropyrum_pernix_K1 Aeropyrum pernix K1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z1N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z1N FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z1n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z1n OCA], [https://pdbe.org/2z1n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z1n RCSB], [https://www.ebi.ac.uk/pdbsum/2z1n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z1n ProSAT]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z1n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z1n OCA], [http://www.ebi.ac.uk/pdbsum/2z1n PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2z1n RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/Q9YDK1_AERPE Q9YDK1_AERPE]
 
== Evolutionary Conservation ==
'''Crystal structure of APE0912 from Aeropyrum pernix K1'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z1/2z1n_consurf.spt"</scriptWhenChecked>
2Z1N is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z1N OCA].  
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==Reference==
  </jmolCheckbox>
A unique catalytic triad revealed by the crystal structure of APE0912, a short-chain dehydrogenase/reductase family protein from Aeropyrum pernix K1., Yamamura A, Ichimura T, Mimoto F, Ohtsuka J, Miyazono K, Okai M, Kamo M, Lee WC, Nagata K, Tanokura M, Proteins. 2008 Mar;70(4):1640-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18175326 18175326]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z1n ConSurf].
[[Category: Aeropyrum pernix]]
<div style="clear:both"></div>
[[Category: Single protein]]
__TOC__
[[Category: Ichimura, T.]]
</StructureSection>
[[Category: Kamo, M.]]
[[Category: Aeropyrum pernix K1]]
[[Category: Lee, W C.]]
[[Category: Large Structures]]
[[Category: Mimoto, F.]]
[[Category: Ichimura T]]
[[Category: Miyazono, K.]]
[[Category: Kamo M]]
[[Category: Nagata, K.]]
[[Category: Lee W-C]]
[[Category: Ohtsuka, J.]]
[[Category: Mimoto F]]
[[Category: Okai, M.]]
[[Category: Miyazono K]]
[[Category: Tanokura, M.]]
[[Category: Nagata K]]
[[Category: Yamamura, A.]]
[[Category: Ohtsuka J]]
[[Category: dehydrogenase]]
[[Category: Okai M]]
[[Category: oxidoreductase]]
[[Category: Tanokura M]]
[[Category: reductase]]
[[Category: Yamamura A]]
[[Category: sdr]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:17:27 2008''

Latest revision as of 13:19, 1 November 2023

Crystal structure of APE0912 from Aeropyrum pernix K1

2z1n, resolution 1.80Å

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