6n7x: Difference between revisions

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'''Unreleased structure'''


The entry 6n7x is ON HOLD
==S. cerevisiae U1 snRNP==
<SX load='6n7x' size='340' side='right' viewer='molstar' caption='[[6n7x]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6n7x]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=5uz5 5uz5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N7X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6N7X FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.6&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6n7x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n7x OCA], [https://pdbe.org/6n7x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6n7x RCSB], [https://www.ebi.ac.uk/pdbsum/6n7x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6n7x ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RU1C_YEAST RU1C_YEAST] Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. YHC1/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.<ref>PMID:10072386</ref> <ref>PMID:12214237</ref> <ref>PMID:9233817</ref>


Authors:  
==See Also==
 
*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]]
Description:  
== References ==
[[Category: Unreleased Structures]]
<references/>
__TOC__
</SX>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Espinosa S]]
[[Category: Hansen KC]]
[[Category: Hill RC]]
[[Category: Jiang J]]
[[Category: Li X]]
[[Category: Liu S]]
[[Category: Zhang L]]
[[Category: Zhao R]]
[[Category: Zhou ZH]]
Retrieved from "https://proteopedia.org/6n7x"