5yc2: Difference between revisions

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==Crystal structure of inner membrane protein Bqt4 in complex with telomeric protein Rap1==
==Crystal structure of inner membrane protein Bqt4 in complex with telomeric protein Rap1==
<StructureSection load='5yc2' size='340' side='right' caption='[[5yc2]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='5yc2' size='340' side='right'caption='[[5yc2]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5yc2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Fission_yeast Fission yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YC2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YC2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5yc2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C] and [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YC2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5YC2 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">bqt4, SPBC19C7.10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=284812 Fission yeast]), rap1, SPBC1778.02 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=284812 Fission yeast])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.704&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5yc2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yc2 OCA], [http://pdbe.org/5yc2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yc2 RCSB], [http://www.ebi.ac.uk/pdbsum/5yc2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yc2 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5yc2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yc2 OCA], [https://pdbe.org/5yc2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5yc2 RCSB], [https://www.ebi.ac.uk/pdbsum/5yc2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5yc2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SMT3_YEAST SMT3_YEAST]] Not known; suppressor of MIF2 mutations. [[http://www.uniprot.org/uniprot/RAP1_SCHPO RAP1_SCHPO]] Involved in the regulation of telomere length, clustering and has a specific role in telomere position effect (TPE). Unlike yeast, exhibits no effect in transcription regulation.<ref>PMID:11676924</ref> <ref>PMID:11676925</ref> <ref>PMID:19948484</ref> 
[https://www.uniprot.org/uniprot/BQT4_SCHPO BQT4_SCHPO] Connects telomeres to the nuclear envelop (NE) during both vegetative growth and meiosis. This connection ensures clustering of telomeres to the spindle pole body (SPB) when cells enter meiotic prophase.<ref>PMID:19948484</ref> [https://www.uniprot.org/uniprot/SMT3_YEAST SMT3_YEAST] Not known; suppressor of MIF2 mutations.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Fission yeast]]
[[Category: Large Structures]]
[[Category: Chen, Y]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Hu, C]]
[[Category: Schizosaccharomyces pombe 972h-]]
[[Category: Choromosome organization]]
[[Category: Chen Y]]
[[Category: Membrane protein]]
[[Category: Hu C]]
[[Category: Nuclear envelope]]
[[Category: Spore formation]]
[[Category: Teleomere bouquet]]
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