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| [[Image:364d.jpg|left|200px]]
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| {{Structure
| | ==3.0 A STRUCTURE OF FRAGMENT I FROM E. COLI 5S RRNA== |
| |PDB= 364d |SIZE=350|CAPTION= <scene name='initialview01'>364d</scene>, resolution 3.000Å
| | <StructureSection load='364d' size='340' side='right'caption='[[364d]], [[Resolution|resolution]] 3.00Å' scene=''> |
| |SITE=
| | == Structural highlights == |
| |LIGAND= <scene name='pdbligand=1SC:5'-O-THIOPHOSPHONOCYTIDINE'>1SC</scene>, <scene name='pdbligand=A:ADENOSINE-5'-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5'-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=G:GUANOSINE-5'-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=U:URIDINE-5'-MONOPHOSPHATE'>U</scene>
| | <table><tr><td colspan='2'>[[364d]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=356d 356d]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=364D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=364D FirstGlance]. <br> |
| |ACTIVITY=
| | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3Å</td></tr> |
| |GENE=
| | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1SC:5-O-THIOPHOSPHONOCYTIDINE'>1SC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| |DOMAIN=
| | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=364d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=364d OCA], [https://pdbe.org/364d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=364d RCSB], [https://www.ebi.ac.uk/pdbsum/364d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=364d ProSAT]</span></td></tr> |
| |RELATEDENTRY=
| | </table> |
| |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=364d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=364d OCA], [http://www.ebi.ac.uk/pdbsum/364d PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=364d RCSB]</span>
| | __TOC__ |
| }}
| | </StructureSection> |
| | | [[Category: Escherichia coli]] |
| '''3.0 A STRUCTURE OF FRAGMENT I FROM E. COLI 5S RRNA'''
| | [[Category: Large Structures]] |
| | | [[Category: Correll CC]] |
| | | [[Category: Freeborn B]] |
| ==Overview==
| | [[Category: Moore PB]] |
| Two new RNA structures portray how non-Watson-Crick base pairs and metal ions can produce a unique RNA shape suitable for recognition by proteins. The crystal structures of a 62 nt domain of E. coli 5S ribosomal RNA and a duplex dodecamer encompassing an internal loop E have been determined at 3.0 and 1.5 A, respectively. This loop E region is distorted by three "cross-strand purine stacks" and three novel, water-mediated noncanonical base pairs and stabilized by a four metal ion zipper. These features give its minor groove a unique hydrogen-bonding surface and make the adjacent major groove wide enough to permit recognition by the ribosomal protein L25, which is expected to bind to this surface.
| | [[Category: Steitz TA]] |
| | |
| ==About this Structure==
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| 364D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. This structure supersedes the now removed PDB entry 356D. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=364D OCA].
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| ==Reference==
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| Metals, motifs, and recognition in the crystal structure of a 5S rRNA domain., Correll CC, Freeborn B, Moore PB, Steitz TA, Cell. 1997 Nov 28;91(5):705-12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9393863 9393863]
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| [[Category: ]] | |
| [[Category: Protein complex]] | |
| [[Category: Correll, C C.]] | |
| [[Category: Freeborn, B.]] | |
| [[Category: Moore, P B.]] | |
| [[Category: Steitz, T A.]] | |
| [[Category: double helix]]
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| [[Category: internal loop]]
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| [[Category: kinked]]
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| [[Category: mismatched]]
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| [[Category: modified]]
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| [[Category: overhanging base]]
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| [[Category: u-rna]]
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| ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:21:52 2008''
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