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==Crystal Structure of the Effector Domain of PhnF from Mycobacterium smegmatis==
==Crystal Structure of the Effector Domain of PhnF from Mycobacterium smegmatis==
<StructureSection load='3f8l' size='340' side='right' caption='[[3f8l]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3f8l' size='340' side='right'caption='[[3f8l]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3f8l]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycs2 Mycs2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F8L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3F8L FirstGlance]. <br>
<table><tr><td colspan='2'>[[3f8l]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_smegmatis_MC2_155 Mycolicibacterium smegmatis MC2 155]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F8L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F8L FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3f8m|3f8m]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MSMEG_0650, phnF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=246196 MYCS2])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f8l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f8l OCA], [https://pdbe.org/3f8l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f8l RCSB], [https://www.ebi.ac.uk/pdbsum/3f8l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f8l ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3f8l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f8l OCA], [http://pdbe.org/3f8l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3f8l RCSB], [http://www.ebi.ac.uk/pdbsum/3f8l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3f8l ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PHNF_MYCS2 PHNF_MYCS2]] Represses the phnDCE operon, involved in the uptake of phosphate, under conditions of phosphate availability in the cell.<ref>PMID:18083811</ref>
[https://www.uniprot.org/uniprot/PHNF_MYCS2 PHNF_MYCS2] Represses the phnDCE operon, involved in the uptake of phosphate, under conditions of phosphate availability in the cell.<ref>PMID:18083811</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Mycs2]]
[[Category: Large Structures]]
[[Category: Baker, E N]]
[[Category: Mycolicibacterium smegmatis MC2 155]]
[[Category: Busby, J N]]
[[Category: Baker EN]]
[[Category: Cook, G M]]
[[Category: Busby JN]]
[[Category: Gebhard, S]]
[[Category: Cook GM]]
[[Category: Lott, S J]]
[[Category: Gebhard S]]
[[Category: Money, V A]]
[[Category: Lott SJ]]
[[Category: Dna-binding]]
[[Category: Money VA]]
[[Category: Gntr]]
[[Category: Hutc]]
[[Category: Phnf]]
[[Category: Regulator]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Utra]]
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