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==Crystal Structure of Helicobacter pylori Heme Oxygenase Hugz in Complex with Heme==
==Crystal Structure of Helicobacter pylori Heme Oxygenase Hugz in Complex with Heme==
<StructureSection load='3gas' size='340' side='right' caption='[[3gas]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='3gas' size='340' side='right'caption='[[3gas]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3gas]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori_nctc_11639 Helicobacter pylori nctc 11639]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GAS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GAS FirstGlance]. <br>
<table><tr><td colspan='2'>[[3gas]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_NCTC_11639 Helicobacter pylori NCTC 11639]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GAS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GAS FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HugZ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=637383 Helicobacter pylori NCTC 11639])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gas OCA], [https://pdbe.org/3gas PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gas RCSB], [https://www.ebi.ac.uk/pdbsum/3gas PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gas ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Heme_oxygenase Heme oxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.99.3 1.14.99.3] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gas OCA], [http://pdbe.org/3gas PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3gas RCSB], [http://www.ebi.ac.uk/pdbsum/3gas PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3gas ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/C0LU01_HELPX C0LU01_HELPX]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ga/3gas_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ga/3gas_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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==See Also==
==See Also==
*[[Heme oxygenase|Heme oxygenase]]
*[[Heme oxygenase 3D structures|Heme oxygenase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Helicobacter pylori nctc 11639]]
[[Category: Helicobacter pylori NCTC 11639]]
[[Category: Heme oxygenase]]
[[Category: Large Structures]]
[[Category: Guo, G]]
[[Category: Guo G]]
[[Category: Guo, Y]]
[[Category: Guo Y]]
[[Category: Hu, Y L]]
[[Category: Hu YL]]
[[Category: Jiang, F]]
[[Category: Jiang F]]
[[Category: Wang, D C]]
[[Category: Wang DC]]
[[Category: Zou, Q M]]
[[Category: Zou QM]]
[[Category: Fmn-binding split barrel]]
[[Category: Oxidoreductase]]

Latest revision as of 09:11, 30 October 2024

Crystal Structure of Helicobacter pylori Heme Oxygenase Hugz in Complex with Heme

3gas, resolution 1.80Å

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