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[[Image:3b7p.gif|left|200px]]


{{Structure
==Crystal structure of spermidine synthase from Plasmodium falciparum in complex with spermine==
|PDB= 3b7p |SIZE=350|CAPTION= <scene name='initialview01'>3b7p</scene>, resolution 2.00&Aring;
<StructureSection load='3b7p' size='340' side='right'caption='[[3b7p]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
|SITE=
== Structural highlights ==
|LIGAND= <scene name='pdbligand=MTA:5&#39;-DEOXY-5&#39;-METHYLTHIOADENOSINE'>MTA</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene>
<table><tr><td colspan='2'>[[3b7p]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B7P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B7P FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Spermidine_synthase Spermidine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.16 2.5.1.16] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
|GENE= PF11_0301 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=36329 Plasmodium falciparum 3D7])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MTA:5-DEOXY-5-METHYLTHIOADENOSINE'>MTA</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b7p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b7p OCA], [https://pdbe.org/3b7p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b7p RCSB], [https://www.ebi.ac.uk/pdbsum/3b7p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b7p ProSAT]</span></td></tr>
|RELATEDENTRY=[[2hte|2HTE]], [[2i7c|2I7C]], [[2pwp|2PWP]]
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3b7p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b7p OCA], [http://www.ebi.ac.uk/pdbsum/3b7p PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3b7p RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/Q8II73_PLAF7 Q8II73_PLAF7]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b7/3b7p_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3b7p ConSurf].
<div style="clear:both"></div>


'''Crystal structure of spermidine synthase from Plasmodium falciparum in complex with spermine'''
==See Also==
 
*[[Spermidine synthase 3D structures|Spermidine synthase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
3B7P is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum_3d7 Plasmodium falciparum 3d7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B7P OCA].
[[Category: Large Structures]]
[[Category: Plasmodium falciparum 3d7]]
[[Category: Plasmodium falciparum 3D7]]
[[Category: Single protein]]
[[Category: Arrowsmith CH]]
[[Category: Spermidine synthase]]
[[Category: Bochkarev A]]
[[Category: Arrowsmith, C H.]]
[[Category: Dong A]]
[[Category: Bochkarev, A.]]
[[Category: Edwards AM]]
[[Category: Dong, A.]]
[[Category: Hui R]]
[[Category: Edwards, A M.]]
[[Category: Kozieradzki I]]
[[Category: Hui, R.]]
[[Category: Lew J]]
[[Category: Kozieradzki, I.]]
[[Category: Plotnikov AN]]
[[Category: Lew, J.]]
[[Category: Qiu W]]
[[Category: Plotnikov, A N.]]
[[Category: Ren H]]
[[Category: Qiu, W.]]
[[Category: Schapira M]]
[[Category: Ren, H.]]
[[Category: Sundstrom M]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Vedadi M]]
[[Category: Schapira, M.]]
[[Category: Wasney G]]
[[Category: Sundstrom, M.]]
[[Category: Weigelt J]]
[[Category: Vedadi, M.]]
[[Category: Wu H]]
[[Category: Wasney, G.]]
[[Category: Zhao Y]]
[[Category: Weigelt, J.]]
[[Category: Wu, H.]]
[[Category: Zhao, Y.]]
[[Category: sgc]]
[[Category: spermidine synthase]]
[[Category: spermine]]
[[Category: structural genomics consortium]]
[[Category: transferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:23:55 2008''

Latest revision as of 12:03, 30 August 2023

Crystal structure of spermidine synthase from Plasmodium falciparum in complex with spermine

3b7p, resolution 2.00Å

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