3hea: Difference between revisions

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==The L29P/L124I mutation of Pseudomonas fluorescens esterase==
==The L29P/L124I mutation of Pseudomonas fluorescens esterase==
<StructureSection load='3hea' size='340' side='right' caption='[[3hea]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3hea' size='340' side='right'caption='[[3hea]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3hea]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_fluorescens_liquefaciens"_flugge_1886 "bacillus fluorescens liquefaciens" flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HEA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HEA FirstGlance]. <br>
<table><tr><td colspan='2'>[[3hea]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_fluorescens Pseudomonas fluorescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HEA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HEA FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EEE:ETHYL+ACETATE'>EEE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hea FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hea OCA], [http://pdbe.org/3hea PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hea RCSB], [http://www.ebi.ac.uk/pdbsum/3hea PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hea ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EEE:ETHYL+ACETATE'>EEE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hea FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hea OCA], [https://pdbe.org/3hea PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hea RCSB], [https://www.ebi.ac.uk/pdbsum/3hea PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hea ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ESTE_PSEFL ESTE_PSEFL]] Bifunctional enzyme, capable of both ester hydrolysis and halogenation. Has a low bromoperoxidase activity. Acts on many phenolic esters.  
[https://www.uniprot.org/uniprot/ESTE_PSEFL ESTE_PSEFL] Bifunctional enzyme, capable of both ester hydrolysis and halogenation. Has a low bromoperoxidase activity. Acts on many phenolic esters.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/he/3hea_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/he/3hea_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus fluorescens liquefaciens flugge 1886]]
[[Category: Large Structures]]
[[Category: Cheeseman, J D]]
[[Category: Pseudomonas fluorescens]]
[[Category: Kazlauskas, R J]]
[[Category: Cheeseman JD]]
[[Category: Morley, K L]]
[[Category: Kazlauskas RJ]]
[[Category: Schrag, J D]]
[[Category: Morley KL]]
[[Category: Alpha/beta hydrolase]]
[[Category: Schrag JD]]
[[Category: Covalent adduct]]
[[Category: Esterase]]
[[Category: Hydrolase]]
[[Category: Oxidoreductase]]
[[Category: Peroxidase]]
[[Category: Tetrahedral intermediate]]
Retrieved from "https://proteopedia.org/3hea"