3bx3: Difference between revisions

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[[Image:3bx3.jpg|left|200px]]


{{Structure
==Puf4 T650C/C724R Mutant bound to Cox17 RNA 3' UTR recognition sequence==
|PDB= 3bx3 |SIZE=350|CAPTION= <scene name='initialview01'>3bx3</scene>, resolution 3.00&Aring;
<StructureSection load='3bx3' size='340' side='right'caption='[[3bx3]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
|SITE= <scene name='pdbsite=AC1:So4+Binding+Site+For+Residue+A+902'>AC1</scene>, <scene name='pdbsite=AC2:So4+Binding+Site+For+Residue+B+903'>AC2</scene>, <scene name='pdbsite=AC3:So4+Binding+Site+For+Residue+A+904'>AC3</scene>, <scene name='pdbsite=AC4:So4+Binding+Site+For+Residue+A+905'>AC4</scene>, <scene name='pdbsite=AC5:So4+Binding+Site+For+Residue+A+906'>AC5</scene>, <scene name='pdbsite=AC6:So4+Binding+Site+For+Residue+B+907'>AC6</scene>, <scene name='pdbsite=AC7:So4+Binding+Site+For+Residue+B+908'>AC7</scene> and <scene name='pdbsite=AC8:So4+Binding+Site+For+Residue+B+909'>AC8</scene>
== Structural highlights ==
|LIGAND= <scene name='pdbligand=A:ADENOSINE-5&#39;-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=G:GUANOSINE-5&#39;-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=U:URIDINE-5&#39;-MONOPHOSPHATE'>U</scene>
<table><tr><td colspan='2'>[[3bx3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BX3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BX3 FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
|GENE= PUF4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bx3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bx3 OCA], [https://pdbe.org/3bx3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bx3 RCSB], [https://www.ebi.ac.uk/pdbsum/3bx3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bx3 ProSAT]</span></td></tr>
|RELATEDENTRY=[[1m6w|1M6W]], [[1m8x|1M8X]], [[1m8y|1M8Y]], [[1m8z|1M8Z]], [[1ib2|1IB2]], [[3bwt|3BWT]], [[3bx2|3BX2]]
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bx3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bx3 OCA], [http://www.ebi.ac.uk/pdbsum/3bx3 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3bx3 RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/PUF4_YEAST PUF4_YEAST] Is not essential for haploid growth, but may affect diploid formation.
 
== Evolutionary Conservation ==
'''Puf4 T650C/C724R Mutant bound to Cox17 RNA 3' UTR recognition sequence'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bx/3bx3_consurf.spt"</scriptWhenChecked>
3BX3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BX3 OCA].  
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3bx3 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Single protein]]
[[Category: Hall TMT]]
[[Category: Hall, T M.T.]]
[[Category: Higgin JJ]]
[[Category: Higgin, J J.]]
[[Category: Miller MT]]
[[Category: Miller, M T.]]
[[Category: ho endonuclease]]
[[Category: puf4]]
[[Category: puf4 t650c c724r mutant]]
[[Category: pumilio]]
[[Category: rna binding]]
[[Category: rna binding protein/rna complex]]
[[Category: transcription]]
 
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